Evaluating the Role of Estrogen Replacement Therapy Combined with Resistance Exercise in Older Women with Knee Osteoarthritis: Insights from a Randomised Clinical Trial

Evaluating the Role of Estrogen Replacement Therapy Combined with Resistance Exercise in Older Women with Knee Osteoarthritis: Insights from a Randomised Clinical Trial

This trial assessed the additive effects of low-dose transdermal estrogen replacement therapy combined with resistance exercise in women aged 65+ with knee osteoarthritis, finding no overall significant benefit but suggesting potential improvements in early-stage disease and mental health.
Modern Pain Neuroscience Approach Versus Usual Care in Chronic Whiplash Disorders: Evidence from a Randomized Clinical Trial

Modern Pain Neuroscience Approach Versus Usual Care in Chronic Whiplash Disorders: Evidence from a Randomized Clinical Trial

This review analyzes a randomized clinical trial comparing modern pain neuroscience approach and usual care physiotherapy in chronic whiplash disorders, highlighting immediate and 12-month improvements, cost-effectiveness, and benefits in anxiety and central sensitization symptoms with MPNA.