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Exploring Combined Finerenone and Empagliflozin Therapy in CKD and Type 2 Diabetes: Baseline Insights from the CONFIDENCE Trial
Posted inDiabetes & Endocrinology Nephrology news Specialties

Exploring Combined Finerenone and Empagliflozin Therapy in CKD and Type 2 Diabetes: Baseline Insights from the CONFIDENCE Trial

Posted by MedXY By MedXY 08/13/2025
The CONFIDENCE trial evaluates whether combining finerenone with empagliflozin more effectively reduces urine albumin-to-creatinine ratio in CKD patients with type 2 diabetes compared to monotherapy, based on baseline characteristics of 818 diverse participants.
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Urine Biomarkers Predict Kidney Function Recovery After Ambulatory Acute Kidney Injury in Blood Pressure Treatment
Posted inClinical Updates Nephrology news Specialties

Urine Biomarkers Predict Kidney Function Recovery After Ambulatory Acute Kidney Injury in Blood Pressure Treatment

Posted by MedXY By MedXY 08/13/2025
Urine biomarkers reflecting glomerular injury and tubular dysfunction can predict kidney function recovery after ambulatory acute kidney injury in hypertensive patients, aiding clinical decision-making during blood pressure management.
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OPTIMAS Trial: Early vs. Delayed Anticoagulation in Acute Ischemic Stroke with Atrial Fibrillation and Chronic Kidney Disease
Posted inCardiology Clinical Updates Nephrology Neurology news Specialties

OPTIMAS Trial: Early vs. Delayed Anticoagulation in Acute Ischemic Stroke with Atrial Fibrillation and Chronic Kidney Disease

Posted by MedXY By MedXY 08/13/2025
The OPTIMAS trial shows that chronic kidney disease does not alter the safety or efficacy of early direct oral anticoagulant use after acute ischemic stroke with atrial fibrillation, supporting early initiation regardless of kidney status.
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Examining the Link Between Obesity and Kidney Outcomes in Heart Failure with Preserved Ejection Fraction
Posted inCardiology Nephrology Specialties

Examining the Link Between Obesity and Kidney Outcomes in Heart Failure with Preserved Ejection Fraction

Posted by MedXY By MedXY 08/11/2025
A pooled analysis of four heart failure trials explores the relationship between obesity and kidney outcomes, revealing waist circumference and waist-to-height ratio as key risk factors, while body mass index showed no significant association.
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ARBs versus Dihydropyridine CCBs : Which Protects the Heart and Which Safeguards the Kidneys?
Posted inCardiology Nephrology news Specialties

ARBs versus Dihydropyridine CCBs : Which Protects the Heart and Which Safeguards the Kidneys?

Posted by MedXY By MedXY 08/10/2025
Comparative review of angiotensin receptor blockers (ARBs, “沙坦”) and dihydropyridine calcium‑channel blockers (DHP‑CCBs, “地平类”) focused on organ protection—kidney, heart and brain—and practical selection based on comorbidity and evidence.
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Dual Renal Protection: Finerenone Plus Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes
Posted inClinical Updates Diabetes & Endocrinology Nephrology news Specialties

Dual Renal Protection: Finerenone Plus Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes

Posted by MedXY By MedXY 08/09/2025
Combining finerenone with empagliflozin provides superior reduction in albuminuria for patients with chronic kidney disease and type 2 diabetes, without increased adverse events.
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Managing Chronic Kidney Disease-Associated Pruritus: Advances and Clinical Strategies
Posted inClinical Updates Medical News Nephrology Specialties

Managing Chronic Kidney Disease-Associated Pruritus: Advances and Clinical Strategies

Posted by MedXY By MedXY 07/30/2025
CKD-associated pruritus affects up to 85% of dialysis patients and significantly impairs quality of life. Stepwise management, including novel therapies like nemolizumab, is essential for effective symptom control and improved patient outcomes.
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