Medxy AI

Decoding the Link Between Pulmonary Artery Pressures and Mortality in Chronic Heart Failure Patients

By MedXY 08/17/2025

Remote monitoring of systolic, diastolic, and mean pulmonary artery pressures predicts 2-year all-cause mortality in chronic heart failure across ejection fraction categories, informing personalized management strategies.

$Cyclosporin Therapy: A Promising Rescue Treatment for Severe Steroid-Refractory Ulcerative Colitis$

Clinical Updates Wellness & Lifestyle

Cyclosporin Therapy: A Promising Rescue Treatment for Severe Steroid-Refractory Ulcerative Colitis

By MedXY 08/17/2025

Cyclosporin demonstrated high clinical response rates in adults with severe steroid-refractory ulcerative colitis, allowing over half to avoid colectomy and highlighting its role as an effective rescue therapy.

Clinical Updates Wellness & Lifestyle

Obicetrapib Shows Promise in Slowing Alzheimer’s Disease Progression Through Lipid Modulation

By MedXY 08/17/2025

Obicetrapib, a CETP inhibitor, significantly slowed Alzheimer’s disease biomarker progression over 12 months and improved p-tau217 levels in APOE4 carriers while also benefiting lipid profiles in cardiovascular disease patients.

Medical News Wellness & Lifestyle

Shield Your Immunity: How Multivitamin-Mineral Supplements Cut Cold and Flu Risks by 42.8%

By MedXY 08/17/2025

A landmark 2025 study reveals that regular multivitamin-mineral supplementation reduces acute respiratory infections by 42.8%, lessening symptoms and boosting immune resilience, especially in adults over 45.

Clinical Updates Wellness & Lifestyle

Synergistic Effects of Metformin and Moderate FODMAP Diet in Improving Postprandial Glycemia and Gut Health in Prediabetes

By MedXY 08/17/2025

Combining metformin with a moderate FODMAP diet improves postprandial glucose control, enhances GLP-1 secretion, increases butyrate-producing gut bacteria, and reduces inflammation without worsening gastrointestinal side effects in prediabetic patients.

Clinical Updates Wellness & Lifestyle

A Single Injection to Regenerate Alveolar Bone: A Breakthrough in Non-Invasive Periodontitis Treatment

By MedXY 08/17/2025

A groundbreaking clinical trial demonstrates that dental pulp stem cell injections can safely and effectively regenerate alveolar bone in chronic periodontitis patients, offering a minimally invasive alternative to surgery.

Medical News Wellness & Lifestyle

Australia Report: Seven Major Challenges of Safe and Reliable Medical Artificial Intelligence in Legislation and Regulation

By MedXY 08/17/2025

This report outlines the challenges and recommendations for implementing AI in healthcare while ensuring safety and responsibility in Australia.

Clinical Updates Wellness & Lifestyle

Long-Term Functional Recovery and Survival after VA-ECMO: Insights from a 26-Center Prospective Cohort Study

By MedXY 08/17/2025

A multicenter study reveals that 30% of adult VA-ECMO patients survive 12 months without new disability, with most disability developing within the first 6 months. Functional independence and employment improve by 12 months post-ECMO.

Clinical Updates Wellness & Lifestyle

Decade-Long Insights into Deferred Versus Immediate Stenting in STEMI Patients: DANAMI-3-DEFER Trial Findings

By MedXY 08/17/2025

The 10-year DANAMI-3-DEFER study compared deferred stenting to immediate stenting in STEMI, showing no mortality benefit but reduced heart failure hospitalizations with deferred stenting.

Clinical Updates Wellness & Lifestyle

Early TAVR Benefits in Asymptomatic Severe Aortic Stenosis: Insights from Cardiac Biomarker Analysis in the EARLY TAVR Trial

By MedXY 08/17/2025

Cardiac biomarkers NT-proBNP and hs-cTnT predict higher risk in asymptomatic severe aortic stenosis, but early TAVR benefits patients regardless of biomarker levels, with greater relative advantage seen in those with lower biomarker concentrations.

Clinical Updates Wellness & Lifestyle

Oral Semaglutide in Type 2 Diabetes: Efficacy and Safety with and without SGLT2 Inhibitors from the SOUL Trial

By MedXY 08/17/2025

The SOUL trial demonstrates that oral semaglutide significantly reduces major cardiovascular events in type 2 diabetes patients, independently of concurrent SGLT2 inhibitor use, with a favorable safety profile.

Clinical Updates Wellness & Lifestyle

Advancements in Transcatheter Edge-to-Edge Repair for Severe Tricuspid Regurgitation: Insights from the TRILUMINATE Pivotal Trial

By MedXY 08/17/2025

Transcatheter edge-to-edge repair (TEER) offers a safe, effective option to reduce tricuspid regurgitation severity, improve quality of life, and lower heart failure hospitalizations up to two years, including in patients with cardiac implantable electronic device leads.

Clinical Updates Wellness & Lifestyle

Inclisiran Shows Promise for Adolescents with Homozygous Familial Hypercholesterolemia: Results from the ORION-13 Trial

By MedXY 08/17/2025

The ORION-13 trial demonstrates that inclisiran significantly lowers LDL cholesterol by 33.3% and is safe and well tolerated in adolescents with homozygous familial hypercholesterolemia, addressing an unmet pediatric treatment need.

Clinical Updates Wellness & Lifestyle

Renal Denervation Shows Sustained Blood Pressure Reduction and Safety Over 24 Months in SPYRAL HTN-ON MED Trial

By MedXY 08/17/2025

The SPYRAL HTN-ON MED trial demonstrates that renal denervation provides significant long-term reductions in both ambulatory and office systolic blood pressure with good safety, supporting its role in managing hypertension.

Clinical Updates Wellness & Lifestyle

Higher Risk of Major Gastrointestinal Bleeding with Edoxaban vs Warfarin After TAVR: Insights from the ENVISAGE-TAVI AF Trial

By MedXY 08/17/2025

The ENVISAGE-TAVI AF trial found that patients with atrial fibrillation undergoing TAVR had a higher incidence of major gastrointestinal bleeding when treated with edoxaban compared to warfarin, highlighting the importance of risk factor identification.

Clinical Updates Wellness & Lifestyle

Edoxaban as a Safe and Effective Anticoagulant Early After Bioprosthetic Valve Replacement: Insights from the ENBALV Trial

By MedXY 08/17/2025

The ENBALV randomized trial demonstrates that edoxaban offers a potential safe and efficacious alternative to warfarin for anticoagulation within three months after surgical bioprosthetic valve replacement, with comparable thromboembolic event rates and a distinct safety profile.

Clinical Updates Wellness & Lifestyle

ADVANTAGE AF Phase 2: Evaluating Pulsed Field Ablation for Persistent Atrial Fibrillation Using Continuous ECG Monitoring

By MedXY 08/17/2025

The ADVANTAGE AF Phase 2 study demonstrates pulsed field ablation's safety and efficacy for persistent atrial fibrillation, introducing continuous cardiac monitoring to better assess arrhythmia burden and outcomes over one year.

Clinical Updates Wellness & Lifestyle

Optimizing Sedation for Pulsed-Field Ablation in Atrial Fibrillation: Results of the COOPERATIVE-PFA Trial

By MedXY 08/17/2025

This randomized trial compares sedation regimens for pulsed-field ablation in atrial fibrillation, finding remimazolam-ketamine deep analgosedation superior to propofol-opioid approaches in reducing hypoxemia and hypotension.

Decoding the Link Between Pulmonary Artery Pressures and Mortality in Chronic Heart Failure Patients

Cyclosporin Therapy: A Promising Rescue Treatment for Severe Steroid-Refractory Ulcerative Colitis

Obicetrapib Shows Promise in Slowing Alzheimer’s Disease Progression Through Lipid Modulation

Shield Your Immunity: How Multivitamin-Mineral Supplements Cut Cold and Flu Risks by 42.8%

Synergistic Effects of Metformin and Moderate FODMAP Diet in Improving Postprandial Glycemia and Gut Health in Prediabetes

A Single Injection to Regenerate Alveolar Bone: A Breakthrough in Non-Invasive Periodontitis Treatment

Australia Report: Seven Major Challenges of Safe and Reliable Medical Artificial Intelligence in Legislation and Regulation

Long-Term Functional Recovery and Survival after VA-ECMO: Insights from a 26-Center Prospective Cohort Study

Decade-Long Insights into Deferred Versus Immediate Stenting in STEMI Patients: DANAMI-3-DEFER Trial Findings

Early TAVR Benefits in Asymptomatic Severe Aortic Stenosis: Insights from Cardiac Biomarker Analysis in the EARLY TAVR Trial

Oral Semaglutide in Type 2 Diabetes: Efficacy and Safety with and without SGLT2 Inhibitors from the SOUL Trial

Advancements in Transcatheter Edge-to-Edge Repair for Severe Tricuspid Regurgitation: Insights from the TRILUMINATE Pivotal Trial

Inclisiran Shows Promise for Adolescents with Homozygous Familial Hypercholesterolemia: Results from the ORION-13 Trial

Renal Denervation Shows Sustained Blood Pressure Reduction and Safety Over 24 Months in SPYRAL HTN-ON MED Trial

Higher Risk of Major Gastrointestinal Bleeding with Edoxaban vs Warfarin After TAVR: Insights from the ENVISAGE-TAVI AF Trial

Edoxaban as a Safe and Effective Anticoagulant Early After Bioprosthetic Valve Replacement: Insights from the ENBALV Trial

ADVANTAGE AF Phase 2: Evaluating Pulsed Field Ablation for Persistent Atrial Fibrillation Using Continuous ECG Monitoring

Optimizing Sedation for Pulsed-Field Ablation in Atrial Fibrillation: Results of the COOPERATIVE-PFA Trial

The Silent Threat of Chagas Disease: Understanding the ‘Kissing Bug’ Epidemic in the U.S.

Ammoxetine Shows Promise as Effective and Well-Tolerated Treatment for Major Depressive Disorder: Insights from a Phase 2 Randomized Trial

Challenges and Insights in Sustaining Weight Loss: Evaluating Adaptive vs Static Support

Evaluating the Patient Health Questionnaire-15 and Somatic Symptom Scale-8: Insights from a Systematic Review and Meta-Analysis