Global Impact of Cardiovascular Risk Factors on Lifetime Cardiovascular Disease Burden and Mortality: A Comprehensive Evidence Synthesis

Global Impact of Cardiovascular Risk Factors on Lifetime Cardiovascular Disease Burden and Mortality: A Comprehensive Evidence Synthesis

This review integrates data from over two million individuals globally, showing that absence of five key cardiovascular risk factors at age 50 confers a life expectancy advantage exceeding a decade, with midlife modification of hypertension and smoking yielding substantial gains in disease-free survival and overall longevity.
Drivers of Human Papillomavirus Vaccine Uptake in Migrant Populations and Interventions to Improve Coverage

Drivers of Human Papillomavirus Vaccine Uptake in Migrant Populations and Interventions to Improve Coverage

This systematic review reveals multifaceted barriers to HPV vaccine uptake among migrants globally, with overall low coverage. It highlights individual, social, and systemic factors influencing uptake and delineates effective culturally tailored strategies to enhance vaccination rates and work towards cervical cancer elimination.
Modern Pain Neuroscience Approach Versus Usual Care in Chronic Whiplash Disorders: Evidence from a Randomized Clinical Trial

Modern Pain Neuroscience Approach Versus Usual Care in Chronic Whiplash Disorders: Evidence from a Randomized Clinical Trial

This review analyzes a randomized clinical trial comparing modern pain neuroscience approach and usual care physiotherapy in chronic whiplash disorders, highlighting immediate and 12-month improvements, cost-effectiveness, and benefits in anxiety and central sensitization symptoms with MPNA.
Protective Effects of High-Intensity Interval Training on Cardiovascular, Neurological, and Metabolic Health: An Evidence-Based Review

Protective Effects of High-Intensity Interval Training on Cardiovascular, Neurological, and Metabolic Health: An Evidence-Based Review

This review synthesizes recent evidence demonstrating that high-intensity interval training (HIIT) confers cardiometabolic benefits, modulates microvascular and neural function, enhances insulin sensitivity, and improves mental health outcomes, underscoring its potential as a multifaceted therapeutic strategy.