PANLAR 2025 Recommendations for Polyarticular Juvenile Idiopathic Arthritis in Latin America — Practical, Evidence-Based Guidance for Resource-Variable Settings
Posted inClinical Updates Wellness & Lifestyle

PANLAR 2025 Recommendations for Polyarticular Juvenile Idiopathic Arthritis in Latin America — Practical, Evidence-Based Guidance for Resource-Variable Settings

PANLAR’s 2025 evidence-based recommendations for non-systemic polyarticular JIA emphasize early treat-to-target care using methotrexate, targeted escalation to biologics when needed, region-sensitive alternatives (leflunomide, triple nbDMARD therapy), and limited steroid bridging to improve outcomes in Latin America.
Clinical Outcomes of Conduction System Pacing vs Right Ventricular Septal Pacing in Atrioventricular Block: Insights from the CSPACE Randomized Controlled Trial
Posted inClinical Updates Wellness & Lifestyle

Clinical Outcomes of Conduction System Pacing vs Right Ventricular Septal Pacing in Atrioventricular Block: Insights from the CSPACE Randomized Controlled Trial

This review synthesizes evidence from the CSPACE RCT demonstrating superior clinical outcomes of conduction system pacing over right ventricular septal pacing in AV block patients, emphasizing reduced pacing-induced cardiomyopathy and CRT upgrade rates.