Fertility-Preserving Hormonal Therapy vs Hysterectomy in Early-Stage Endometrial Cancer: Survival Outcomes and Clinical Implications

Fertility-Preserving Hormonal Therapy vs Hysterectomy in Early-Stage Endometrial Cancer: Survival Outcomes and Clinical Implications

This analysis compares survival in young women with early-stage endometrial cancer treated with fertility-preserving hormonal therapy versus hysterectomy, highlighting survival equivalence in women under 40 years and increased mortality risk in older patients undergoing hormonal therapy.
Precision Psychiatry Roadmap: Integrating Biology into Mental Disorder Classification and Treatment

Precision Psychiatry Roadmap: Integrating Biology into Mental Disorder Classification and Treatment

Mental disorders currently diagnosed symptomatically can be redefined using biology-informed frameworks integrating biological, behavioral, and environmental data. The Precision Psychiatry Roadmap aims to harmonize global research and clinical efforts to improve diagnostics and develop mechanism-based treatments.
Impact of Maternal Trace Element Levels on Neonatal Growth Among Diabetic and Non-Diabetic Pregnancies

Impact of Maternal Trace Element Levels on Neonatal Growth Among Diabetic and Non-Diabetic Pregnancies

A case–control study reveals that elevated copper levels in diabetic pregnant women negatively affect newborn weight and head circumference, while chromium correlates positively with birth length. Smoking exposure adversely impacts infants’ weight, underscoring maternal trace element status and lifestyle as key determinants of neonatal outcomes.