Global Variations in Patient Radiation Exposure for Coronary Artery Disease Diagnosis: A Synthesized Review of the INCAPS 4 Findings

Global Variations in Patient Radiation Exposure for Coronary Artery Disease Diagnosis: A Synthesized Review of the INCAPS 4 Findings

This review analyzes global radiation doses in CAD diagnostic imaging based on the INCAPS 4 study. It highlights significant disparities across modalities and regions, revealing that patients in low-income countries and those undergoing CCTA face substantially higher radiation risks, necessitating urgent standardized protocols.
Beyond Objective Responses: Amivantamab Demonstrates Significant Clinical Benefit in Recurrent Adenoid Cystic Carcinoma

Beyond Objective Responses: Amivantamab Demonstrates Significant Clinical Benefit in Recurrent Adenoid Cystic Carcinoma

A Phase 2 clinical trial of amivantamab, an EGFR-MET bispecific antibody, in recurrent or metastatic adenoid cystic carcinoma (ACC) showed a 72.2% clinical benefit rate. While the primary objective response rate was low, the high rate of disease stabilization highlights its potential in managing this rare malignancy.