Urgent Surgery Versus Fibrinolytic Therapy in Left-Sided Prosthetic Valve Thrombosis: Insights from a Groundbreaking Randomized Trial
Posted inClinical Updates Emergency Medicine General Surgery news

Urgent Surgery Versus Fibrinolytic Therapy in Left-Sided Prosthetic Valve Thrombosis: Insights from a Groundbreaking Randomized Trial

This first randomized trial comparing urgent surgery and fibrinolytic therapy (low-dose t-PA) for symptomatic left-sided prosthetic valve thrombosis finds similar efficacy but higher mortality with surgery and higher residual valve dysfunction with fibrinolysis.
Long-term Stroke Risk in Chinese Adults with Newly Diagnosed Diabetes and Impaired Glucose Tolerance: Insights from the 34-Year Da Qing Diabetes Study
Posted inClinical Updates Diabetes & Endocrinology Neurology news Specialties

Long-term Stroke Risk in Chinese Adults with Newly Diagnosed Diabetes and Impaired Glucose Tolerance: Insights from the 34-Year Da Qing Diabetes Study

A 34-year follow-up of the Da Qing Diabetes Study reveals significantly increased stroke incidence among Chinese adults with newly diagnosed type 2 diabetes and impaired glucose tolerance, highlighting the beneficial impact of lifestyle intervention, particularly in women.
Theta Burst Stimulation of the Temporo-Parietal Cortex for Persistent Auditory Hallucinations in Schizophrenia: A Comprehensive Review of a Phase 3 Randomised Multicentre Trial and Contextual Evidence
Posted inClinical Updates news Psychiatry

Theta Burst Stimulation of the Temporo-Parietal Cortex for Persistent Auditory Hallucinations in Schizophrenia: A Comprehensive Review of a Phase 3 Randomised Multicentre Trial and Contextual Evidence

This review synthesizes evidence on bilateral continuous theta burst stimulation (cTBS) of the temporo-parietal cortex for persistent auditory verbal hallucinations (AVH) in schizophrenia, focusing on a landmark German phase 3 trial demonstrating safety and modest efficacy.
Enhancing Malaria Control in West Africa: Combining Non-Pyrethroid Indoor Residual Spraying or Intensive Behaviour Change Communication with Long-Lasting Insecticidal Nets
Posted inClinical Updates Public Health Specialties

Enhancing Malaria Control in West Africa: Combining Non-Pyrethroid Indoor Residual Spraying or Intensive Behaviour Change Communication with Long-Lasting Insecticidal Nets

This trial shows that adding non-pyrethroid indoor residual spraying (IRS) or intensive behaviour change communication (BCC) to long-lasting insecticidal nets (LLINs) reduces malaria incidence by over 20% in West African rural communities, highlighting promising integrated malaria control strategies.