Medxy AI

Harnessing Machine Learning to Predict High-Risk Coronary Artery Disease: Insights from the SCOT-HEART Trial

By MedXY 09/14/2025

Machine learning models trained on clinical data improve prediction of coronary artery disease on CT scans compared to traditional risk scores, potentially guiding better resource utilization in cardiovascular care.

Clinical Updates Wellness & Lifestyle

Harnessing AI: LLM-Based Conversational Agents Reduce Depression and Anxiety Among Young Adults in Short Video App Trial

By MedXY 09/14/2025

A 28-day RCT demonstrates that a conversational AI trained on a large language model effectively reduces mild depression and anxiety symptoms in young adults through dialog interventions integrated in short video apps.

Clinical Updates Wellness & Lifestyle

AI-Assisted Optical Diagnosis in Colonoscopy: Ensuring Safety While Reducing Unnecessary Polypectomies

By MedXY 09/14/2025

A randomized trial demonstrates that leaving small non-neoplastic colorectal polyps in situ with AI-assisted optical diagnosis is as safe and effective as systematic removal, supporting less invasive colonoscopy strategies.

Wellness & Lifestyle

Lower Your Blood Pressure by 8 mmHg in Just 10 Minutes a Day: The Power of Isometric Exercises

By MedXY 09/14/2025

Isometric exercises, a form of static muscle engagement, can lower blood pressure as effectively as some medications, offering a simple, drug-free way to protect your heart and vessels.

Medical News Wellness & Lifestyle

The Hidden Vascular Assassin: How Homocysteine Independently Accelerates Atherosclerosis

By MedXY 09/14/2025

Beyond cholesterol and blood pressure, homocysteine silently hardens arteries, driving cardiovascular disease progression independently—latest research reveals its biomechanical impact and prevention strategies.

Medical News Wellness & Lifestyle

The Hidden Threat in Your Mouth: How Oral Bacteria Can Trigger Heart Attacks

By MedXY 09/14/2025

New research reveals that common oral bacteria, particularly Viridans streptococci, can infiltrate arterial plaques, increasing the risk of heart attacks by triggering inflammation and plaque rupture.

Clinical Updates Wellness & Lifestyle

Oral Corticosteroids Fail to Improve Recovery in Vocal Fold Paralysis After Thyroid Surgery: Insights from a Randomized Clinical Trial

By MedXY 09/13/2025

A randomized trial shows that a 7-day course of oral corticosteroids does not enhance vocal fold remobilization or voice quality in unilateral vocal fold paralysis following thyroid or parathyroid surgery, underscoring the continued importance of speech therapy.

Clinical Updates Wellness & Lifestyle

Optimizing Colorectal Cancer Screening Outreach for Adults Aged 45-49: Insights From a Large-Scale Randomized Trial

By MedXY 09/13/2025

A large UCLA Health randomized clinical trial found that usual care via mailed FIT outreach outperformed active choice strategies in colorectal cancer screening uptake among adults aged 45 to 49 years, highlighting the challenges in engaging younger populations in screening programs.

Clinical Updates Wellness & Lifestyle

Accelerating Depression Recovery: The Impact of Measurement-Based Care in Pakistan’s Low-Resource Settings

By MedXY 09/13/2025

A randomized clinical trial in Pakistan demonstrates that measurement-based care accelerates antidepressant treatment response and remission in major depressive disorder compared to standard care, underscoring its potential in low-resource settings.

Clinical Updates Wellness & Lifestyle

Evaluating Peer Coaching for Weight Management in Primary Care: Insights from a VA-Based Cluster Randomized Clinical Trial

By MedXY 09/13/2025

A cluster randomized trial in veterans assessed peer coaching for weight management, showing improved program attendance but no significant 12-month weight loss difference versus enhanced usual care.

Clinical Updates Wellness & Lifestyle

Personalized High-Definition Transcranial Direct Current Stimulation: A Promising Rapid Intervention for Moderate to Severe Depression

By MedXY 09/13/2025

A randomized clinical trial demonstrates that personalized high-definition transcranial direct current stimulation (HD-tDCS) significantly improves mood in patients with moderate to severe depression, showing faster and comparable effect sizes to conventional therapies and also reducing anxiety symptoms.

Clinical Updates Wellness & Lifestyle

Unexpected Risks of Postoperative 20% Albumin Infusion in High-Risk Cardiac Surgery Patients: Insights from the ALBICS AKI Trial

By MedXY 09/13/2025

The ALBICS AKI trial reveals that postoperative infusion of 20% albumin increases acute kidney injury risk in high-risk cardiac surgery patients, challenging prior assumptions about albumin's nephroprotective role in this setting.

Clinical Updates Wellness & Lifestyle

Finerenone Efficacy and Safety Across Frailty Levels in Heart Failure: Insights from the FINEARTS-HF Trial

By MedXY 09/13/2025

This analysis of the FINEARTS-HF trial reveals that finerenone reduces cardiovascular death and heart failure worsening regardless of frailty status, without increasing adverse events, supporting its use in frail patients with HFmrEF or HFpEF.

Clinical Updates Wellness & Lifestyle

CT Angiography Enhances Lifestyle and Prevention Uptake in Cardiovascular Risk Management: Insights from SCOT-HEART 2 Substudy

By MedXY 09/13/2025

A nested substudy from SCOT-HEART 2 reveals coronary CT angiography modestly improves healthy lifestyle adherence, preventive therapy acceptance, and risk factor modification compared to traditional cardiovascular risk scoring in asymptomatic individuals at risk.

Clinical Updates Wellness & Lifestyle

Preoperative versus Postoperative Stereotactic Radiation Therapy for Brain Metastases: Safety, Feasibility, and Efficiency Insights from a Phase 3 Randomized Trial

By MedXY 09/13/2025

A phase 3 randomized trial demonstrates that preoperative stereotactic radiation therapy (SRT) for brain metastases offers comparable safety and reduced treatment duration compared to postoperative SRT, potentially improving patient care logistics.

Clinical Updates Wellness & Lifestyle

Early ctDNA Dynamics Predict Long-Term Survival in dMMR/MSI-H Metastatic Colorectal Cancer Treated With Immune Checkpoint Inhibitors

By MedXY 09/13/2025

Change in circulating tumor DNA (ctDNA) one month after treatment initiation predicts progression-free and overall survival in patients with dMMR/MSI-H metastatic colorectal cancer receiving immune checkpoint inhibitors, offering a potential biomarker for therapeutic decision-making.

Clinical Updates Wellness & Lifestyle

Induction vs Adjuvant Chemoradiotherapy in High-Risk N2-N3 Nasopharyngeal Carcinoma: Insights from a Phase 3 Randomized Trial

By MedXY 09/12/2025

This phase 3 trial compares induction-concurrent chemotherapy with concurrent-adjuvant chemotherapy in high-risk N2 to N3 nasopharyngeal carcinoma, finding no significant difference in 3-year progression-free survival while highlighting distinct safety profiles.

Clinical Updates Wellness & Lifestyle

Intercostal Nerve Block: A Viable Alternative to Thoracic Epidural for Pain Control in Lung Surgery

By MedXY 09/12/2025

This randomized trial demonstrates that single-shot intercostal nerve block offers noninferior pain relief compared to thoracic epidural analgesia after thoracoscopic lung resection, with benefits in opioid reduction, mobility, and shorter hospitalization.

Clinical Updates Wellness & Lifestyle

Deep Learning Prediction of Retinal Nerve Fiber Layer Thickness as a Novel Risk Biomarker for Glaucoma in Ocular Hypertension

By MedXY 09/12/2025

A novel deep learning model predicted retinal nerve fiber layer thickness from optic disc photos, enabling risk stratification for primary open-angle glaucoma in ocular hypertension patients, with baseline and longitudinal changes strongly correlated with disease conversion.

Clinical Updates Wellness & Lifestyle

U-BOMB Phase 2 Trial: Promising Activity of Utidelone Plus Bevacizumab in ERBB2-Negative Metastatic Breast Cancer with Active Brain Metastases

By MedXY 09/12/2025

The U-BOMB phase 2 trial demonstrates that the combination of utidelone and bevacizumab shows encouraging efficacy and tolerability in patients with ERBB2-negative metastatic breast cancer and active brain metastases, addressing a critical unmet clinical need.

Harnessing Machine Learning to Predict High-Risk Coronary Artery Disease: Insights from the SCOT-HEART Trial

Harnessing AI: LLM-Based Conversational Agents Reduce Depression and Anxiety Among Young Adults in Short Video App Trial

AI-Assisted Optical Diagnosis in Colonoscopy: Ensuring Safety While Reducing Unnecessary Polypectomies

Lower Your Blood Pressure by 8 mmHg in Just 10 Minutes a Day: The Power of Isometric Exercises

The Hidden Vascular Assassin: How Homocysteine Independently Accelerates Atherosclerosis

The Hidden Threat in Your Mouth: How Oral Bacteria Can Trigger Heart Attacks

Oral Corticosteroids Fail to Improve Recovery in Vocal Fold Paralysis After Thyroid Surgery: Insights from a Randomized Clinical Trial

Optimizing Colorectal Cancer Screening Outreach for Adults Aged 45-49: Insights From a Large-Scale Randomized Trial

Accelerating Depression Recovery: The Impact of Measurement-Based Care in Pakistan’s Low-Resource Settings

Evaluating Peer Coaching for Weight Management in Primary Care: Insights from a VA-Based Cluster Randomized Clinical Trial

Personalized High-Definition Transcranial Direct Current Stimulation: A Promising Rapid Intervention for Moderate to Severe Depression

Unexpected Risks of Postoperative 20% Albumin Infusion in High-Risk Cardiac Surgery Patients: Insights from the ALBICS AKI Trial

Finerenone Efficacy and Safety Across Frailty Levels in Heart Failure: Insights from the FINEARTS-HF Trial

CT Angiography Enhances Lifestyle and Prevention Uptake in Cardiovascular Risk Management: Insights from SCOT-HEART 2 Substudy

Preoperative versus Postoperative Stereotactic Radiation Therapy for Brain Metastases: Safety, Feasibility, and Efficiency Insights from a Phase 3 Randomized Trial

Early ctDNA Dynamics Predict Long-Term Survival in dMMR/MSI-H Metastatic Colorectal Cancer Treated With Immune Checkpoint Inhibitors

Induction vs Adjuvant Chemoradiotherapy in High-Risk N2-N3 Nasopharyngeal Carcinoma: Insights from a Phase 3 Randomized Trial

Intercostal Nerve Block: A Viable Alternative to Thoracic Epidural for Pain Control in Lung Surgery

Deep Learning Prediction of Retinal Nerve Fiber Layer Thickness as a Novel Risk Biomarker for Glaucoma in Ocular Hypertension

U-BOMB Phase 2 Trial: Promising Activity of Utidelone Plus Bevacizumab in ERBB2-Negative Metastatic Breast Cancer with Active Brain Metastases

Immunogenicity and Safety of the VLA15 Lyme Borreliosis Vaccine Across Age Groups: A Phase 2 Randomised Controlled Trial and Integrative Review

MACRO Trial Insights: Endoscopic Sinus Surgery Outperforms Clarithromycin in Chronic Rhinosinusitis Management

Adjunctive Corticosteroids in Severe Pneumocystis jirovecii Pneumonia Among HIV-negative Patients: Insights from a Multicentre Randomised Trial

Evaluating BDLC Regimen in Pre-XDR Tuberculosis: Findings from the endTB-Q Phase 3 Trial