What is Ashwagandha?
Ashwagandha, also known as Withania somnifera, Indian ginseng, contains various active components beneficial to human health. It can help alleviate stress, enhance immune function, improve sleep, boost energy levels, and protect cardiovascular health. However, it may also have side effects such as gastrointestinal discomfort, allergic reactions, hormonal imbalances, interference with medications, and drowsiness. Below are detailed insights on its benefits and potential risks.
Health Benefits of Ashwagandha:
1. Stress Relief
Ashwagandha possesses adaptogenic properties, meaning it can help the body manage stress better. It modulates hormonal levels in the body, particularly cortisol, which is closely linked to the body’s stress response. By balancing cortisol levels, it can reduce feelings of anxiety and tension, promoting an improved mental state.
2. Enhanced Immune Function
Rich in a variety of nutrients and bioactive substances, this herb can stimulate immune cell activity and enhance the body’s immune response. Regular use may help the body fend off pathogens more effectively, consequently reducing the risk of illness.
3. Improved Sleep Quality
Ashwagandha has a calming effect on the nervous system, helping relax both the mind and body, which may lead to better sleep quality. For those who suffer insomnia due to stress or anxiety, this herb may serve as a supportive treatment, facilitating a smoother transition into deep sleep.
4. Increased Energy Levels
This herb can enhance physical endurance and energy levels. It promotes metabolism and boosts muscle strength, thereby increasing vitality during daily activities and physical exercise, while also reducing fatigue.
5. Cardiovascular Protection
Certain components in Ashwagandha help regulate blood lipid levels and blood pressure, reducing cholesterol deposits in blood vessel walls and lowering the risk of atherosclerosis, thus offering protective benefits for cardiovascular health.
Potential Side Effects of Ashwagandha:
1. Gastrointestinal Discomfort
Some individuals may experience gastrointestinal issues such as nausea, vomiting, diarrhea, or abdominal discomfort after taking Ashwagandha. This can occur due to irritation of the gastrointestinal tract, potentially affecting normal digestive function.
2. Allergic Reactions
Individuals allergic to Ashwagandha may experience allergic reactions upon exposure. Symptoms can include rashes, itching, and difficulty breathing; severe reactions can be life-threatening. Therefore, those with allergies should use caution.
3. Hormonal Disruption
Given Ashwagandha’s ability to regulate hormones, excessive use may lead to hormonal imbalances in the body. For instance, it may affect thyroid function and lead to abnormal secretion of thyroid hormones, subsequently impacting metabolism and normal bodily functions.
4. Medication Interactions
Ashwagandha may interact with certain medications, either enhancing or diminishing their effects and affecting how they are metabolized in the body. Individuals taking other medications should consult a physician before using this herb to avoid potential drug interactions.
5. Drowsiness
This herb can have sedative effects, and excessive consumption may cause drowsiness or dizziness, impacting daily functioning. This can be particularly disruptive for individuals who need to maintain high levels of concentration at work.
Precautions When Using Ashwagandha:
When considering the use of Ashwagandha in daily life, it is essential to consult a doctor or herbalist, especially for people with pre-existing health conditions, those taking medications, pregnant women, or breastfeeding mothers. It is important to adhere strictly to the recommended dosages to avoid excessive intake. Additionally, monitoring bodily responses is crucial; if discomfort arises, use should be stopped immediately and medical assistance sought.
References
Ramapalaniappan A, Loganathan V, Morde A, Padigaru M, Patni P, Joshua L, Thomas JV. Superior Bioavailability of a Novel 1.5% Ashwagandha Formulation (Zenroot™): A Randomized, Double-Blind, Single-Dose, Comparative, Oral Bioavailability Study in Healthy Adults. Adv Ther. 2025 Aug 1. doi: 10.1007/s12325-025-03292-7 IF: 4.0 Q1 . Epub ahead of print. PMID: 40748423 IF: 4.0 Q1 .
Alhasani RH, Alsharif I, Albalawi AE, Albalawi FE, Mohammedsaleh ZM, Saleh FM, Barnawi J, Alshammari NS, Basoudan NS, Ghouth NM, Almohaimeed HM, Hasan T, Ellatif SA, Soliman MH. Anti-inflammatory and anti-diabetic role of Ashwagandha (Withania somnifera) in a type 2 diabetes mellitus mouse model: a study using histological, molecular, and pathological parameters. Protoplasma. 2025 Jul 28. doi: 10.1007/s00709-025-02096-4 IF: 2.5 Q2 . Epub ahead of print. PMID: 40717151 IF: 2.5 Q2 .
Tariq T, Yousaf A, Sandhu MA, Riaz A, Khan A, Akram AW, Hussain SM, Moaeen-Ud-Din M, Anees S, Naheed G, Khan IA, Rhee MH, Saba E. A comprehensive guide on the anti-inflammatory activities of Asgand Nagori (Withania somnifera) with special reference to cinnamaldehyde and carvacrol. Sci Rep. 2025 Jul 2;15(1):23243. doi: 10.1038/s41598-025-05998-8 IF: 3.9 Q1 . PMID: 40603373 IF: 3.9 Q1 ; PMCID: PMC12223241 IF: 3.9 Q1 .
Ewa J, Klusiewicz A, Rębiś K, Długołęcka B, Charmas M, Cieśliński I. Effects of an 8-week high intensity interval training (HIIT) and ashwagandha supplementation on aerobic capacity, muscle oxygenation and haematological parameters in healthy men. Biol Sport. 2025 Feb 4;42(3):129-139. doi: 10.5114/biolsport.2025.147453 IF: 5.0 Q1 . PMID: 40657001 IF: 5.0 Q1 ; PMCID: PMC12244407 IF: 5.0 Q1 .
Wiciński M, Fajkiel-Madajczyk A, Sławatycki J, Szambelan M, Szyperski P, Wojciechowski P, Wójcicki J, Gawryjołek M. Ashwagandha (Withania somnifera) and Its Effects on Well-Being-A Review. Nutrients. 2025 Jun 27;17(13):2143. doi: 10.3390/nu17132143 IF: 5.0 Q1 . PMID: 40647248 IF: 5.0 Q1 ; PMCID: PMC12252077 IF: 5.0 Q1 .
Gokdemir GS, Seker U, Baksi N, Baylan M, Demirtaş B, Gokdemir MT. Antidepressant-like effects of Ashwagandha (Withania Somnifera) on chronic unpredictable mild stress-induced depression in adolescent rats. Psychopharmacology (Berl). 2025 Jun 25. doi: 10.1007/s00213-025-06844-5 IF: 3.3 Q2 . Epub ahead of print. PMID: 40560204 IF: 3.3 Q2 .
Tancreda G, Ravera S, Panfoli I. Preclinical Evidence of Withania somnifera and Cordyceps spp.: Neuroprotective Properties for the Management of Alzheimer’s Disease. Int J Mol Sci. 2025 Jun 4;26(11):5403. doi: 10.3390/ijms26115403 IF: 4.9 Q1 . PMID: 40508211 IF: 4.9 Q1 ; PMCID: PMC12156217 IF: 4.9 Q1 .
