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Predicting the Path to Dementia: Five-Year Progression from Mild to Major Vascular Cognitive Impairment Following Ischemic Stroke
Posted inInternal Medicine Neurology news

Predicting the Path to Dementia: Five-Year Progression from Mild to Major Vascular Cognitive Impairment Following Ischemic Stroke

Posted by MedXY By MedXY 02/17/2026
A five-year prospective study reveals that 13.6% of stroke patients with mild cognitive impairment progress to major VCI, identifying age, diabetes, atrial fibrillation, and small vessel disease as key predictors for long-term cognitive decline.
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Tau Links Amyloid and Vascular Burden to Faster Clinical Decline: Chronicity Reveals Synergy Between White Matter Injury and Amyloid in Dementia Progression
Posted inNeurology news

Tau Links Amyloid and Vascular Burden to Faster Clinical Decline: Chronicity Reveals Synergy Between White Matter Injury and Amyloid in Dementia Progression

Posted by MedXY By MedXY 11/05/2025
Longer years above amyloid and white matter hyperintensity positivity predict faster clinical decline. White matter vascular burden amplifies amyloid-related progression, and tau accumulation mediates this effect, highlighting targets and timing for intervention.
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