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Sequential Chemoradiotherapy vs Induction Plus Concurrent Chemoradiotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma: Efficacy and Safety Insights from a Phase 3 Randomized Trial
Posted inClinical Updates Oncology Radiology Specialties

Sequential Chemoradiotherapy vs Induction Plus Concurrent Chemoradiotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma: Efficacy and Safety Insights from a Phase 3 Randomized Trial

Posted by By MedXY 08/23/2025
A multicenter phase 3 trial demonstrates that sequential chemoradiotherapy is noninferior to induction plus concurrent chemoradiotherapy for stage III/IVA nasopharyngeal carcinoma with fewer acute toxicities.
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Early Toxicity Comparison of Moderately Hypofractionated Radiotherapy and Stereotactic Body Radiotherapy in Prostate Cancer: Insights from the PACE-C Trial
Posted inClinical Updates news Oncology Radiology Specialties Urology

Early Toxicity Comparison of Moderately Hypofractionated Radiotherapy and Stereotactic Body Radiotherapy in Prostate Cancer: Insights from the PACE-C Trial

Posted by By MedXY 08/03/2025
The PACE-C phase 3 trial shows that stereotactic body radiotherapy (SBRT) and moderately hypofractionated radiotherapy (MHRT) have comparable early toxicity profiles in intermediate- and high-risk prostate cancer patients.
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Antibody-Drug Conjugates in Breast Cancer: Efficacy, Toxicity, and Evolving Management Strategies
Posted inClinical Updates news Oncology Specialties

Antibody-Drug Conjugates in Breast Cancer: Efficacy, Toxicity, and Evolving Management Strategies

Posted by By MedXY 07/30/2025
Antibody-drug conjugates (ADCs) have transformed breast cancer therapy but bring notable toxicity risks. This review examines the clinical evidence, adverse event management, and future directions for optimizing ADC use.
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  • Prior Osteotomy Lowers Implant Survival and Raises TKA Complexity — but Early Pain and Function Are Similar: Insights from 189,932 Dutch Arthroplasties
  • Wearables and Behaviour Change Work Best: Physical Activity Interventions After Hip and Knee Arthroplasty Improve Steps but Not Sedentary Time
  • Valgus Bracing Lowers Medial Tibiofemoral Cartilage Pressure and Shifts Load Laterally in Varus Knee Osteoarthritis
  • T2 Mapping Detects BMI-Linked Cartilage Changes and Lateral Compartment Signal Differences in Population-Based Knee OA
  • Partitioning Knee Osteoarthritis Genetic Risk by BMI Association Clarifies Prediction and Mechanisms
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