thrombectomy – Medxy AI

Optimizing Head Positioning in Large Vessel Occlusion Stroke Before Thrombectomy: Evidence from a Randomized Clinical Trial

By MedXY 09/11/2025

A recent randomized clinical trial demonstrates that 0° head-of-bed positioning prior to thrombectomy in patients with large vessel occlusion stroke preserves neurological stability and reduces mortality compared to the conventional 30° elevation.

Clinical Updates Wellness & Lifestyle

Thrombolysis Before Thrombectomy May Raise ICH Risk After Stroke: A Comprehensive Review of Recent Evidence

By MedXY 08/19/2025

A meta-analysis of over 2000 stroke patients found that intravenous thrombolysis (IVT) before endovascular treatment (EVT) modestly increases intracranial hemorrhage (ICH) risk, especially in patients with elevated glucose and blood pressure, though functional benefits may still outweigh risks.

Clinical Updates Wellness & Lifestyle

Unexplained Early Neurologic Deterioration After Thrombectomy in Stroke: Incidence, Risk Factors, and Mechanistic Insights

By MedXY 08/17/2025

Unexplained early neurologic deterioration (unEND) affects about 10% of ischemic stroke patients after thrombectomy, linked to age, anesthesia, delayed reperfusion, and infarct growth beyond hypoperfused tissue.

Clinical Updates

Tenecteplase in Modern Stroke Care: Comparative Insights from Recent Chinese Clinical Trials

By MedXY 08/01/2025

Three major Chinese trials examine intravenous and intra-arterial tenecteplase as adjuncts to thrombectomy in acute large-vessel occlusion stroke, revealing functional benefit with intravenous use before thrombectomy but not after reperfusion.

Clinical Updates Wellness & Lifestyle

Intra-arterial Tenecteplase After Thrombectomy for Acute Stroke: Interpreting the ANGEL-TNK Randomized Clinical Trial

By MedXY 07/31/2025

The ANGEL-TNK trial found that intra-arterial tenecteplase after successful endovascular thrombectomy improved excellent neurological outcomes at 90 days without increasing bleeding or mortality, but secondary outcomes showed no significant benefit.

Clinical Updates Wellness & Lifestyle

Intra-arterial Tenecteplase After Thrombectomy for Acute Stroke: Interpreting the ANGEL-TNK Randomized Clinical Trial

By MedXY 07/31/2025