TAVI – Medxy AI

Head-to-Head Comparison of SAPIEN 3 and Myval Transcatheter Heart Valves in TAVI: Insights from the COMPARE-TAVI 1 Trial

By MedXY 09/07/2025

The COMPARE-TAVI 1 trial demonstrates non-inferiority of Myval transcatheter heart valves compared to SAPIEN 3 THVs at 1-year post-TAVI for a composite clinical endpoint in severe aortic stenosis patients.

Clinical Updates Wellness & Lifestyle

Minimizing Anesthesia in Transcatheter Aortic Valve Implantation: Insights from the DOUBLE-CHOICE Trial

By MedXY 09/07/2025

The DOUBLE-CHOICE randomized trial demonstrates non-inferiority of isolated local anesthesia versus conscious sedation in transfemoral TAVI, suggesting a safe minimalist anesthesia strategy with potential trade-offs in patient comfort.

Clinical Updates Wellness & Lifestyle

Cerebral Embolic Protection and Cognitive Outcomes After TAVI: Insights from the BHF PROTECT-TAVI Trial

By MedXY 09/06/2025

The BHF PROTECT-TAVI randomized trial found no cognitive benefit from using cerebral embolic protection devices during transcatheter aortic valve implantation, despite their theoretical role in mitigating embolic brain injury.

Clinical Updates Wellness & Lifestyle

Cerebral Embolic Protection Fails to Preserve Cognitive Function After TAVI: Insights from the BHF PROTECT-TAVI Trial

By MedXY 09/06/2025

The BHF PROTECT-TAVI randomized trial reveals that cerebral embolic protection (CEP) devices do not prevent cognitive decline following transcatheter aortic valve implantation (TAVI), challenging assumptions about their neuroprotective benefits.

Medical News Wellness & Lifestyle

TAVI vs SAVR at Low–Intermediate Risk: What the New Individual‑Patient Meta‑Analysis Means for Practice

By MedXY 08/31/2025

A patient‑level meta‑analysis of randomized trials finds transcatheter aortic valve implantation (TAVI) reduces 1‑year risk of death or stroke versus surgical AVR in low– to intermediate‑risk patients—informing patient selection, heart‑team decisions, and follow‑up priorities.

Clinical Updates Wellness & Lifestyle

Percutaneous versus Surgical Approaches in Aortic Stenosis with Complex Coronary Disease: TCW Trial Insights

By MedXY 08/02/2025

The TCW trial demonstrates that FFR-guided PCI plus TAVI is non-inferior and even superior to SAVR plus CABG in elderly patients with severe aortic stenosis and complex coronary artery disease.

Clinical Updates Wellness & Lifestyle

Routine Use of Cerebral Embolic Protection in TAVI: Evidence, Outcomes, and Clinical Implications

By MedXY 08/01/2025

Large-scale trials show that routine cerebral embolic protection during TAVI does not significantly reduce early stroke rates, though selective benefits in major stroke and secondary outcomes may exist.