safety – Medxy AI

Epaminurad: A Promising hURAT1 Inhibitor for Effective and Safe Gout Management – Insights from a Phase 2b Dose-Finding Trial

By MedXY 08/26/2025

Epaminurad significantly lowers serum urate levels in gout patients with excellent safety, offering a promising alternative to existing therapies. This randomized controlled trial identifies optimal dosing and confirms tolerability over 12 weeks.

Clinical Updates Wellness & Lifestyle

Low-Dose Oral Minoxidil: Safe from Tachycardia Risk in Large Alopecia Cohort

By MedXY 08/19/2025

A large retrospective study of over 524,000 patients found no increased risk of tachycardia associated with low-dose oral minoxidil (≤5 mg/day) for nonscarring hair loss, supporting its cardiac safety profile in patients without preexisting cardiac conditions.

Clinical Updates Wellness & Lifestyle

Mechanical Thrombectomy in Distal Medium MCA Occlusion: Impact of Pre-Stroke Low-Dose Aspirin on Efficacy and Safety

By MedXY 08/17/2025

Pre-stroke low-dose aspirin in distal medium vessel occlusion stroke patients undergoing mechanical thrombectomy is linked to improved 90-day functional outcomes and reduced mortality without increased symptomatic hemorrhage risk.

Clinical Updates Wellness & Lifestyle

Edaravone Dexborneol in Acute Ischemic Stroke: Real-World Evidence of Enhanced Functional Recovery and Safety

By MedXY 08/17/2025

In a large multicenter cohort study, edaravone dexborneol treatment in acute ischemic stroke patients was linked to improved 90-day functional outcomes without increased adverse events, supporting its clinical utility.

Clinical Updates Wellness & Lifestyle

Durable Remission and Safety of Upadacitinib in Moderate to Severe Ulcerative Colitis: Insights from the Phase 3 U-ACTIVATE Long-Term Extension Interim Analysis

By MedXY 08/14/2025

Interim data from the U-ACTIVATE study demonstrate sustained clinical and endoscopic remission and a consistent safety profile for upadacitinib up to 3 years in moderate to severe ulcerative colitis.

Clinical Updates

Real-World Safety and Effectiveness of MVA-BN Vaccination Against Mpox: Evidence from German, Systematic Review, and Immunogenicity Cohorts

By MedXY 08/03/2025

MVA-BN vaccination is safe and effective against mpox in at-risk populations, but reduced protection is noted in people living with HIV. Dose strategies and patient immunological status may affect outcomes.

Medical News Wellness & Lifestyle

Benzene in Acne Products: Clinical Implications, Risks, and Regulatory Response

By MedXY 07/31/2025

Recent findings of benzene in benzoyl peroxide acne products have sparked debate, recalls, and regulatory scrutiny, prompting calls for improved safety measures despite the continued clinical utility of these therapies.