prophylactic antibiotics

Prophylactic Strategies to Prevent Infection in Lower Limb Peripheral Arterial Reconstruction: Evidence and Clinical Implications

By MedXY 12/17/2025

Cochrane review shows prophylactic antibiotics may reduce SSI risk in peripheral arterial reconstruction; closed incision negative pressure therapy offers possible benefit but evidence is low.

Infectious Diseases news OB/GYN & Women's Health

Prophylactic Antibiotics in Episiotomy and Second Degree Tears: Insights from the REPAIR Trial

By MedXY 10/31/2025

The REPAIR study demonstrates that prophylactic antibiotics reduce clinically relevant wound complications after episiotomy or second degree tears, highlighting a potential role for antibiotics in postpartum care.

Clinical Updates news

Assessing the Value of Preoperative Antibiotics in Uncomplicated Acute Appendicitis: Insights from the PERFECT-Antibiotics Trial

By MedXY 09/28/2025

Preoperative antibiotics in uncomplicated acute appendicitis do not reduce appendiceal perforation risk but lower surgical site infections. This large multicenter trial clarifies their limited role while awaiting timely appendectomy.