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PGT-A for Severe Male Infertility: Reducing Pregnancy Loss Without Boosting Live Birth Rates
Posted innews Urology

PGT-A for Severe Male Infertility: Reducing Pregnancy Loss Without Boosting Live Birth Rates

Posted by MedXY By MedXY 01/22/2026
A multicentre RCT published in the BMJ demonstrates that while PGT-A does not increase cumulative live birth rates for couples with severe male infertility, it significantly reduces the risk of pregnancy loss, providing a nuanced framework for clinical counseling.
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Rethinking Mosaicism: Why Reporting Putative Mosaic Embryos Fails to Improve IVF Outcomes
Posted innews OB/GYN & Women's Health

Rethinking Mosaicism: Why Reporting Putative Mosaic Embryos Fails to Improve IVF Outcomes

Posted by MedXY By MedXY 12/24/2025
A large, double-blinded study reveals that reporting embryo mosaicism (ICN) during PGT-A provides no meaningful clinical predictive value for live birth rates, suggesting that current classification systems may unnecessarily limit embryo selection without improving overall success in routine IVF practice.
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