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Mechanotransduction in Congestive Hepatopathy: The Integrin αV-YAP-CTGF Axis as a Driver of Fibrosis and Carcinogenesis
Posted inClinical Updates Gastroenterology news

Mechanotransduction in Congestive Hepatopathy: The Integrin αV-YAP-CTGF Axis as a Driver of Fibrosis and Carcinogenesis

Posted by MedXY By MedXY 03/18/2026
This review synthesizes recent findings on how mechanical stress in congestive hepatopathy activates the Integrin αV-YAP-CTGF pathway in liver sinusoidal endothelial cells, leading to fibrosis and liver cancer.
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