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Incident Splenomegaly: Defining Clinical Thresholds for Hematologic Cancer and Liver Disease Risk
Posted inGastroenterology news Oncology

Incident Splenomegaly: Defining Clinical Thresholds for Hematologic Cancer and Liver Disease Risk

Posted by MedXY By MedXY 01/27/2026
This large-scale prospective cohort study identifies specific spleen length and volume thresholds that significantly increase the 5-year risk of hematologic malignancies and liver disease, providing a data-driven framework for clinical workup of incidental findings.
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Elafibranor Shows Promise as a Safe and Effective Therapy for Primary Sclerosing Cholangitis: Insights from the Phase II ELMWOOD Trial
Posted inGastroenterology news

Elafibranor Shows Promise as a Safe and Effective Therapy for Primary Sclerosing Cholangitis: Insights from the Phase II ELMWOOD Trial

Posted by MedXY By MedXY 10/29/2025
The phase II ELMWOOD trial demonstrates that elafibranor, a dual PPAR-α/δ agonist, is well tolerated and significantly improves biochemical markers in patients with primary sclerosing cholangitis over 12 weeks, warranting further investigation.
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Persistent High Mortality in Severe Alcohol-Associated Hepatitis: Insights from a Five-Decade Meta-Analysis
Posted inGastroenterology Internal Medicine news

Persistent High Mortality in Severe Alcohol-Associated Hepatitis: Insights from a Five-Decade Meta-Analysis

Posted by MedXY By MedXY 10/09/2025
This meta-analysis reveals that short-term mortality in severe alcohol-associated hepatitis remains high, with no significant improvement over the past four decades despite advances in care, underscoring the urgent need for better therapies and prognostic strategies.
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Seven Groups Who Should Avoid Fish Oil: Essential Precautions You Must Know
Posted inFamily Medicine & Nutrition news Specialties

Seven Groups Who Should Avoid Fish Oil: Essential Precautions You Must Know

Posted by MedXY By MedXY 08/08/2025
Fish oil offers health benefits but is not suitable for everyone. Learn about the seven groups who should avoid fish oil to prevent health risks and ensure safe supplement use.
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Severe Childhood Obesity Linked to Elevated Health Risks
Posted inDiabetes & Endocrinology news Pediatrics Specialties

Severe Childhood Obesity Linked to Elevated Health Risks

Posted by MedXY By MedXY 07/25/2025
A new study highlights the growing prevalence of extreme pediatric obesity in the U.S. and its association with serious metabolic and cardiovascular health risks, emphasizing the need for targeted interventions.
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  • Challenging the Label: Large-Scale Meta-Analysis Refutes Most Statin-Attributed Adverse Effects
  • Tenecteplase Improves 90-Day Functional Outcomes in Basilar Artery Occlusion Within a 24-Hour Window: Results from TRACE-5
  • Beyond Symptom Resolution: Physiological Recovery Lags Behind Subjective Wellness in COVID-19 and Influenza
  • Early Inpatient Initiation of 1-Month TB Preventive Therapy Proves Non-Inferior for Patients with Advanced HIV and Cryptococcal Meningitis
  • Systematic Complication Management Boosts Long-Term Survival in Pancreatic Cancer: Insights from the PORSCH Trial
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