Triglyceride Glucose-Waist Height Ratio Index as a Predictor of Cardiometabolic Multimorbidity in Chinese Middle-Aged and Older Adults: Insights from a National Prospective Cohort Study
Posted inCardiology Diabetes & Endocrinology Specialties

Triglyceride Glucose-Waist Height Ratio Index as a Predictor of Cardiometabolic Multimorbidity in Chinese Middle-Aged and Older Adults: Insights from a National Prospective Cohort Study

This study demonstrates that the triglyceride glucose-waist height ratio (TyG-WHtR) index independently predicts cardiometabolic multimorbidity risk in Chinese adults aged ≥45, showing a linear dose-response relationship and improved predictive performance over traditional metrics.
Joint Impact of TyG-Related Indices and eGDR on Cardiometabolic Multimorbidity Risk in Chinese Adults: Insights from a Nationwide Cohort
Posted inCardiology Diabetes & Endocrinology news

Joint Impact of TyG-Related Indices and eGDR on Cardiometabolic Multimorbidity Risk in Chinese Adults: Insights from a Nationwide Cohort

This study elucidates that high triglyceride glucose (TyG) related indices combined with low estimated glucose disposal rate (eGDR) synergistically elevate cardiometabolic multimorbidity (CMM) risk in middle-aged and older Chinese adults, enhancing early risk stratification and prevention strategies.
Revealing Metabolic Subtypes in Gestational Diabetes Using Dynamic OGTT-Derived C-Peptide Trajectories: Implications for Personalized Risk and Management
Posted inClinical Updates Diabetes & Endocrinology news OB/GYN & Women's Health Specialties

Revealing Metabolic Subtypes in Gestational Diabetes Using Dynamic OGTT-Derived C-Peptide Trajectories: Implications for Personalized Risk and Management

Dynamic C-peptide patterns during OGTT uncover metabolic heterogeneity in GDM, identifying insulin-resistant women at risk for fetal overgrowth and normoglycemic women at risk for preeclampsia, suggesting improved stratified treatment beyond glucose-based diagnosis.
Dissecting Depression in Diabetes: Distinct Links of Somatic and Cognitive Symptoms with Inflammation and Insulin Resistance
Posted inClinical Updates Diabetes & Endocrinology Internal Medicine news Psychiatry Specialties

Dissecting Depression in Diabetes: Distinct Links of Somatic and Cognitive Symptoms with Inflammation and Insulin Resistance

New GRADE sub-study reveals that somatic symptoms of depression, not cognitive-affective symptoms, are chiefly associated with inflammation and insulin resistance in type 2 diabetes, highlighting a pathophysiological bridge for targeted interventions.