HPV vaccine – Medxy AI

One Dose of HPV Vaccine Noninferior to Two: Implications for Global Cervical Cancer Prevention

By MedXY 12/03/2025

A randomized trial of 20,330 girls 12–16 years shows one dose of bivalent or nonavalent HPV vaccine prevents persistent HPV16/18 infection as effectively as two doses over 5 years, with high effectiveness and no safety signals.

Infectious Diseases news Public Health

Immunogenicity and HPV Infection After One, Two, and Three Doses of Quadrivalent HPV Vaccine in Indian Girls: A Multicentre Prospective Cohort Study

By MedXY 11/24/2025

This study evaluates immune responses and HPV infection rates in Indian girls after receiving one, two, or three doses of the quadrivalent HPV vaccine, supporting WHO’s recommendation for two doses spaced at least six months apart.

Infectious Diseases news Public Health

Single-dose Cervarix induces durable seropositivity but fails HPV‑16 GMC non-inferiority versus three-dose Gardasil-4: implications from the PRIMAVERA immunobridging trial

By MedXY 11/24/2025

PRIMAVERA immunobridging shows single-dose Cervarix induces near-universal seropositivity at 36 months and non-inferior HPV-18 antibodies versus three-dose Gardasil-4, but HPV-16 antibody GMCs were lower; results inform but do not yet support regulatory single-dose approval.

OB/GYN & Women's Health Oncology Specialties

Seventeen Years On: Robust Population-Level Effectiveness and Herd Protection from HPV Vaccination in High-Risk Young Women

By MedXY 09/29/2025

Seventeen years after HPV vaccine introduction, substantial reductions in vaccine-type HPV prevalence confirm strong effectiveness and herd protection among vaccinated and unvaccinated sexually experienced adolescent girls and young women at high risk for HPV.

Medical News OB/GYN & Women's Health Oncology Specialties

Beyond Cervical Cancer: The Rising Threat of HPV-Linked Oropharyngeal Cancer in Men

By MedXY 09/09/2025

HPV-related oropharyngeal cancer incidence has surpassed cervical cancer, with men facing a 5-10 fold higher risk. Understanding this shift, symptoms, risks, and the critical role of HPV vaccination can transform prevention and early detection.

news OB/GYN & Women's Health Public Health Specialties

Drivers of Human Papillomavirus Vaccine Uptake in Migrant Populations and Interventions to Improve Coverage

By MedXY 08/19/2025

This systematic review reveals multifaceted barriers to HPV vaccine uptake among migrants globally, with overall low coverage. It highlights individual, social, and systemic factors influencing uptake and delineates effective culturally tailored strategies to enhance vaccination rates and work towards cervical cancer elimination.