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Comparative Effectiveness of Dolutegravir/Lamivudine Versus Bictegravir/Emtricitabine/Tenofovir Alafenamide for Maintenance Therapy in HIV: Insights from the PASO-DOBLE Trial
Posted inClinical Updates HIV/AIDS news Specialties

Comparative Effectiveness of Dolutegravir/Lamivudine Versus Bictegravir/Emtricitabine/Tenofovir Alafenamide for Maintenance Therapy in HIV: Insights from the PASO-DOBLE Trial

Posted by MedXY By MedXY 08/03/2025
The PASO-DOBLE trial demonstrated non-inferiority of dolutegravir/lamivudine versus bictegravir/FTC/TAF for maintenance in virologically suppressed HIV-1 adults, with similar efficacy and safety over 48 weeks.
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Advances in Second-Line Antiretroviral Therapy for Children with HIV in Africa: Insights from the CHAPAS-4 Trial
Posted inClinical Updates HIV/AIDS news Specialties

Advances in Second-Line Antiretroviral Therapy for Children with HIV in Africa: Insights from the CHAPAS-4 Trial

Posted by MedXY By MedXY 08/02/2025
TAF–emtricitabine and dolutegravir-based regimens outperform standard options as second-line ART for African children with HIV, offering improved viral suppression and safety.
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Novel HIV Peptides Identified During Treatment Interruption May Inform Next-Generation Therapeutic Strategies
Posted inClinical Updates HIV/AIDS news Specialties

Novel HIV Peptides Identified During Treatment Interruption May Inform Next-Generation Therapeutic Strategies

Posted by MedXY By MedXY 07/30/2025
Discovery of genetically conserved, mutation-intolerant HIV peptides in rebound virus during analytic treatment interruption highlights new avenues for mRNA vaccine development and functional HIV cure strategies.
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Assessing Antibiotic Use During Pregnancy: Impact on Birth Outcomes in HIV Contexts
Posted inHIV/AIDS news Specialties

Assessing Antibiotic Use During Pregnancy: Impact on Birth Outcomes in HIV Contexts

Posted by MedXY By MedXY 07/29/2025
A clinical study reveals that trimethoprim-sulfamethoxazole does not significantly improve infant birth weight or related outcomes in HIV-positive pregnancies.
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  • Beyond Concentration: The MUCQ Score Redefines Chronic Bronchitis Identification
  • Maternal Nipocalimab Therapy for Severe HDFN: Evidence of Neonatal Safety and Immunological Recovery
  • Wearable TEAS Device Outperforms Metoclopramide for Moderate to Severe Postoperative Nausea and Vomiting
  • Decoding Antidepressant Response: Genetic and Phenotypic Markers of Treatment Complexity and Sustained Use
  • Substantial Residual Risk and High Costs Persist in HFrEF Despite Optimal Quadruple Therapy at Discharge
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