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More is Not Always Better: The GOULASH Trial Challenges High-Energy Early Nutrition in Acute Pancreatitis
Posted inGastroenterology Internal Medicine news

More is Not Always Better: The GOULASH Trial Challenges High-Energy Early Nutrition in Acute Pancreatitis

Posted by MedXY By MedXY 03/07/2026
The multicentre GOULASH trial reveals that high-energy nutrition in the early phase of acute pancreatitis does not improve outcomes and may increase risks of organ failure and pain relapse compared to a gradual caloric increase, leading to the trial's early termination for futility.
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Supplemental Donor Human Milk Did Not Speed Full Enteral Feeding in Moderate–Late Preterm Infants: Results From a Multisite Randomized Trial
Posted innews Pediatrics

Supplemental Donor Human Milk Did Not Speed Full Enteral Feeding in Moderate–Late Preterm Infants: Results From a Multisite Randomized Trial

Posted by MedXY By MedXY 12/14/2025
In a blinded multisite RCT of 201 moderate–late preterm infants, short-term supplementation with pasteurized donor human milk versus term formula did not shorten time to full enteral feeds; donor milk was associated with slower regain of birth weight.
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Full Milk Feeds From Day 1 in Late Preterm Infants: Large RCT Shows No Shorter Hospital Stay and No Signal for Increased NEC or Hypoglycaemia
Posted innews Pediatrics

Full Milk Feeds From Day 1 in Late Preterm Infants: Large RCT Shows No Shorter Hospital Stay and No Signal for Increased NEC or Hypoglycaemia

Posted by MedXY By MedXY 12/01/2025
The FEED1 trial randomized 2088 infants born at 30+0 to 32+6 weeks to full enteral feeds from day 1 versus gradual feeding with IV support. Full feeds did not shorten hospital stay and showed no increase in necrotising enterocolitis or clinically important hypoglycaemia.
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