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Oral Regimens for Whipple’s Disease: A Non-Inferiority Trial of Doxycycline-Hydroxychloroquine Versus Standard Intravenous Therapy
Posted inClinical Updates Wellness & Lifestyle

Oral Regimens for Whipple’s Disease: A Non-Inferiority Trial of Doxycycline-Hydroxychloroquine Versus Standard Intravenous Therapy

Posted by By MedXY 08/03/2025
A German phase 2/3 trial found oral doxycycline-hydroxychloroquine as effective and safe as standard intravenous ceftriaxone followed by oral trimethoprim-sulfamethoxazole for Whipple’s disease, potentially transforming outpatient management.
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Doxycycline Post-Exposure Prophylaxis Significantly Reduces Bacterial STIs Among MSM and Transgender Women: Final Results from the DoxyPEP Trial
Posted inClinical Updates Wellness & Lifestyle

Doxycycline Post-Exposure Prophylaxis Significantly Reduces Bacterial STIs Among MSM and Transgender Women: Final Results from the DoxyPEP Trial

Posted by By MedXY 08/02/2025
The DoxyPEP trial demonstrates that doxycycline post-exposure prophylaxis markedly lowers bacterial STI incidence in men who have sex with men and transgender women, with good tolerability and minimal resistance over 12 months.
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