cognitive decline

Quit Smoking Anytime: How Stopping in Midlife Can Preserve Your Memory and Thinking Skills

By MedXY 11/01/2025

New research reveals that quitting smoking in mid to late life significantly slows cognitive decline, offering an added three years of brain health regardless of quitting age.

Neurology news Psychiatry

Unlocking the Predictive Power of Plasma Biomarkers for Early Alzheimer’s Disease Detection

By MedXY 10/27/2025

This review evaluates recent evidence on plasma AD biomarkers, especially phosphorylated tau217 and amyloid PET, for predicting cognitive decline in unimpaired individuals, highlighting their potential and limitations.

Neurology Pathology & Lab Medicine Specialties

APOE4 Amplifies Blood Biomarkers’ Association with Cognitive Decline in Aging Adults: Insights from a Biracial 20-Year Cohort Study

By MedXY 10/21/2025

This study reveals that APOE4 carriers with elevated blood neurodegenerative biomarkers experience accelerated cognitive decline, highlighting the gene's role in exacerbating neurodegeneration among community-dwelling older adults without dementia.

Family Medicine & Nutrition Neurology news Specialties

APOE ε4 Allele: A Key Driver of Cognitive Decline and Neurodegeneration in Older Adults from the Democratic Republic of the Congo

By MedXY 10/21/2025

This study reveals that the APOE ε4 allele is linked to increased dementia prevalence, cognitive deficits, brain atrophy, and plasma biomarkers of neurodegeneration in older adults in the DRC, emphasizing its critical role in African populations.

Neurology news Public Health

Optimizing Lifestyle Interventions to Prevent Cognitive Decline in Older Adults: Insights from a Comprehensive Network Meta-Analysis

By MedXY 10/20/2025

A large-scale network meta-analysis highlights that combined physical exercise and cognitive training most effectively improve cognition in older adults without impairment, emphasizing tailored lifestyle strategies for dementia prevention.

Neurology news Public Health

Mid-to-Late-Life Smoking Cessation Slows Long-Term Cognitive Decline: Insights from a 12-Country Longitudinal Study

By MedXY 10/20/2025

Smoking cessation in middle-aged and older adults is linked to a slower decline in memory and fluency over six years, suggesting quitting smoking benefits long-term cognitive health regardless of age at cessation.

Clinical Updates news Pediatrics Psychiatry Specialties

Childhood Loneliness: A Lasting Risk Factor for Cognitive Decline and Dementia in Later Life

By MedXY 09/24/2025

Childhood loneliness significantly increases the risk of cognitive decline and dementia in middle-aged and older adults, independent of adult loneliness, highlighting the importance of early psychosocial interventions.

Diabetes & Endocrinology Neurology news Specialties

Unlocking Precision Nutrition: Genetic Insights from the MIND Diet Trial for Cognitive Health

By MedXY 09/16/2025

This article explores the genetic data resource from the MIND trial, highlighting its potential to tailor dietary interventions to mitigate cognitive decline and advance precision nutrition for Alzheimer's risk populations.

Family Medicine & Nutrition Medical News Neurology news Specialties

How B Vitamins Can Slow Brain Shrinkage and Prevent Dementia？

By MedXY 09/11/2025

Long-term studies reveal that proper supplementation of B vitamins can slow brain atrophy, improve cognitive function, and reduce dementia risk, especially in older adults at risk of deficiency.

Clinical Updates news OB/GYN & Women's Health Specialties

Top Ten Research Priorities in Menopause: A Comprehensive Evidence-Based Review

By MedXY 09/07/2025

This review synthesizes the Menopause Priority Setting Partnership findings, highlighting the top ten evidence-based research priorities addressing non-hormonal treatments, lifestyle interventions, cognitive and sleep changes, hormone therapy duration, global experiences, breast cancer management, dementia risk, and personalized hormone therapy safety.

Family Medicine & Nutrition Neurology news Specialties

13 Brain-Boosting Foods to Help Fight Dementia: Are You Eating These?

By MedXY 08/26/2025

Discover 13 scientifically-supported foods that can help protect and enhance cognitive function, potentially reducing dementia risk as you age.

Clinical Updates Neurology news Specialties

Nine-Year Outcomes After Lacunar and Mild Cortical Ischemic Stroke: Long-Term Functional, Cognitive, and Vascular Impacts

By MedXY 08/26/2025

This longitudinal study reveals persistent cognitive, physical, and vascular challenges up to 9 years after minor lacunar or cortical ischemic stroke, emphasizing different risks and recovery patterns by stroke subtype.

Clinical Updates Family Medicine & Nutrition Neurology news Radiology Specialties

Physical Exercise Slows Neurodegeneration and Cognitive Decline in Early Parkinson Disease: Insights from Longitudinal MRI Analysis

By MedXY 08/24/2025

Regular physical activity in early Parkinson disease patients is linked to slower brain atrophy in temporoparietal and limbic regions, mediating better preservation of memory and attention over four years.

Clinical Updates Neurology news Specialties

Unlocking Parkinson’s Prognosis: The Role of α-Synuclein Seed Amplification Kinetics

By MedXY 08/16/2025

A longitudinal study reveals that α-synuclein seed amplification assay kinetic measures enhance diagnostic accuracy and predict cognitive decline in Parkinson’s disease, independent of Alzheimer's co-pathology.

Clinical Updates Family Medicine & Nutrition news Specialties

Structured vs Self-Guided Multidomain Lifestyle Interventions for Cognitive Health: Insights from the US POINTER Randomized Clinical Trial

By MedXY 07/30/2025

A large US trial found that structured, intensive lifestyle interventions led to greater improvements in global cognition over two years compared to self-guided approaches among older adults at risk for cognitive decline.

Clinical Updates Medical News

Structured Lifestyle Intervention Shows Superior Cognitive Benefits in At-Risk Older Adults: Insights from the US POINTER Trial

By MedXY 07/29/2025

A large US trial shows that intensive, structured lifestyle programs yield greater cognitive improvement in at-risk older adults compared to self-guided approaches, though both are beneficial.

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The Essential Role of Vitamin B12: Recognizing Symptoms and Managing Deficiency

By MedXY 07/26/2025

Vitamin B12 deficiency can lead to serious health issues, including anemia and cognitive decline. Learn who is at risk and how to manage this deficiency.