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Heart Failure Mortality: The Resilient Challenge in an Era of Declining Cardiovascular Deaths
Posted inCardiology Diabetes & Endocrinology news

Heart Failure Mortality: The Resilient Challenge in an Era of Declining Cardiovascular Deaths

Posted by MedXY By MedXY 12/20/2025
This multi-national analysis of 2.92 million deaths highlights a concerning trend: while coronary and stroke mortality have plummeted, heart failure mortality remains stagnant or rising, with people with diabetes bearing a disproportionate and unchanging excess risk over the last two decades.
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Reassessing the Role of Steroidal Mineralocorticoid Receptor Antagonists in Dialysis Patients: Safety and Efficacy Insights from a Systematic Review and Meta-Analysis
Posted inCardiology Nephrology news

Reassessing the Role of Steroidal Mineralocorticoid Receptor Antagonists in Dialysis Patients: Safety and Efficacy Insights from a Systematic Review and Meta-Analysis

Posted by MedXY By MedXY 10/11/2025
Steroidal mineralocorticoid receptor antagonists show minimal impact on cardiovascular mortality in dialysis patients, with limited safety concerns and evidence gaps in subgroups and non-steroidal agents.
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Reevaluating Mortality Risks: The Paradox of Low Apolipoprotein B and LDL-Cholesterol Levels in Cardiovascular Health
Posted inCardiology Clinical Updates news

Reevaluating Mortality Risks: The Paradox of Low Apolipoprotein B and LDL-Cholesterol Levels in Cardiovascular Health

Posted by MedXY By MedXY 09/24/2025
This study finds an unexpected association between low levels of apolipoprotein B and LDL-cholesterol with increased all-cause and cardiovascular mortality, highlighting the complex role of lipid markers in mortality risk assessment.
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Risks and Realities of Withdrawing Heart Failure Medications After Ejection Fraction Improvement
Posted inCardiology news Specialties

Risks and Realities of Withdrawing Heart Failure Medications After Ejection Fraction Improvement

Posted by MedXY By MedXY 08/17/2025
Withdrawal of renin-angiotensin inhibitors and mineralocorticoid receptor antagonists in patients with heart failure and improved ejection fraction significantly increases 1-year cardiovascular mortality and hospitalization risks; beta-blocker withdrawal shows varied effects based on EF.
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  • NT-501 Encapsulated Cell Therapy Successfully Slows Photoreceptor Loss in Macular Telangiectasia Type 2: Results from Two Phase 3 Trials
  • Beyond the Golden Years: Young COPD and Early Lung Function Decline as Critical Drivers of Premature Mortality and Cardiovascular Risk
  • High Efficacy of Pemigatinib in Myeloid/Lymphoid Neoplasms with FGFR1 Rearrangement: Insights from the FIGHT-203 Trial
  • IL-13 Inhibition with Cendakimab: A New Frontier in Eosinophilic Esophagitis Management
  • Post-PCI Troponin Kinetics Reveal Hemorrhagic Transformation as a Critical Driver of In-Hospital Mortality in STEMI
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