cardiometabolic risk

Semaglutide Mitigates Cardiometabolic Risk in Early-Stage Schizophrenia: Insights from a Randomized Clinical Trial

By MedXY 02/11/2026

A landmark RCT demonstrates that adjunctive semaglutide significantly improves glycemic control and induces substantial weight loss in individuals with schizophrenia spectrum disorders treated with second-generation antipsychotics, potentially closing the mortality gap in this high-risk population.

Cardiology Diabetes & Endocrinology news

Tirzepatide Lowers 10‑Year Predicted Risk of Cardiovascular Disease and Type 2 Diabetes in Adults with Obesity and Prediabetes: Post hoc Analysis of SURMOUNT‑1

By MedXY 12/05/2025

A post hoc analysis of the three‑year SURMOUNT‑1 trial found that once‑weekly tirzepatide (5–15 mg) produced dose‑dependent reductions in 10‑year predicted risks for ASCVD, heart failure, total CVD and progression to type 2 diabetes versus placebo in adults with obesity and prediabetes.

Cardiology news Psychiatry

Not All Antidepressants Are the Same: Differential Cardiometabolic and Physiological Effects from a Large Network Meta‑analysis

By MedXY 11/11/2025

A 151‑trial network meta‑analysis of 58,534 participants shows marked differences among 30 antidepressants in weight, blood pressure, heart rate, lipids, glucose and liver enzymes; findings support individualized choice and targeted baseline and follow‑up monitoring.

Cardiology news Pediatrics Public Health Specialties

Trends in Body Composition and Cardiometabolic Risk Factors in Spanish Children Over Three Decades

By MedXY 10/05/2025

This article reviews a 30-year study from Spain analyzing body composition and cardiometabolic risk factors in children aged 8-11, showing obesity plateauing, lipid improvements, blood pressure reductions, but rising insulin levels from 1992 to 2022.

Cardiology Diabetes & Endocrinology Medical News news Specialties

Multifunctional Dietary Approach to Reduce Intestinal Inflammation in Cardiometabolic Risk Subjects: Insights from the SINFONI Project

By MedXY 08/11/2025

This article explores how a multifunctional dietary strategy can alleviate intestinal inflammation linked to cardiometabolic risk by modifying gut microbiota composition.

Cardiology Diabetes & Endocrinology Medical News news Specialties

Preterm Birth Linked to Long-Term Adult Cardiometabolic and Mental Health Risks: New U.S. Cohort Study

By MedXY 07/30/2025

Adults born preterm face significantly higher risks of cardiometabolic abnormalities and internalizing mental health problems by age 35, according to a new U.S. cohort study.