Beyond Picky Eating: Large-Scale Study Reveals the Genetic Architecture and Developmental Impact of ARFI Phenotypes

Beyond Picky Eating: Large-Scale Study Reveals the Genetic Architecture and Developmental Impact of ARFI Phenotypes

This large-scale study of 35,751 children characterizes ARFI phenotypes, revealing a 6.3% clinical prevalence and significant genetic heritability. Findings link ARFI to the ADCY3 locus and long-term neurodevelopmental difficulties, emphasizing the need for early identification and broad support interventions.
High Burden of ARFID Symptoms in Adults with Disorders of Gut–Brain Interaction: A Population-Based Study Signals Need for Routine Screening

High Burden of ARFID Symptoms in Adults with Disorders of Gut–Brain Interaction: A Population-Based Study Signals Need for Routine Screening

A 2023 population survey of 4,002 adults in the UK and US found that positive screens for avoidant/restrictive food intake disorder (ARFID) were common among people with disorders of gut–brain interaction (DGBI) and associated with greater health burden, underweight, poorer quality of life, and higher healthcare use.