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Unraveling Depressive Symptom Trajectories in Early Adolescents: Insights from a 12-Month Cohort in Nanchong, China
Posted innews Psychiatry Public Health

Unraveling Depressive Symptom Trajectories in Early Adolescents: Insights from a 12-Month Cohort in Nanchong, China

Posted by By MedXY 10/30/2025
This longitudinal study reveals distinct trajectories of depressive symptoms among Chinese adolescents, highlighting key sociodemographic and behavioral predictors that can inform early intervention strategies.
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From Adolescence to Adulthood: The Lasting Impact of Dysmenorrhoea on Chronic Pain Risk
Posted inOB/GYN & Women's Health Public Health

From Adolescence to Adulthood: The Lasting Impact of Dysmenorrhoea on Chronic Pain Risk

Posted by By MedXY 10/19/2025
A UK cohort study reveals that adolescent dysmenorrhoea increases the risk of chronic pain in adulthood, highlighting the need for early identification and management.
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Progression of Transdiagnostic Clinical Stages From Childhood to Young Adulthood: Evidence and Implications
Posted innews Pediatrics Specialties

Progression of Transdiagnostic Clinical Stages From Childhood to Young Adulthood: Evidence and Implications

Posted by By MedXY 09/28/2025
This review synthesizes cohort and longitudinal studies supporting the progression of transdiagnostic mental health stages from familial risk in childhood through early symptoms in adolescence to clinically significant disorders in young adulthood, independent of early life confounders.
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Does Increasing Cigarette Use Stabilize Mood? Insights from a 6-Year Real-Time Adolescent Study
Posted inPediatrics Psychiatry Public Health Specialties

Does Increasing Cigarette Use Stabilize Mood? Insights from a 6-Year Real-Time Adolescent Study

Posted by By MedXY 08/25/2025
Longitudinal observational data reveal that as adolescents increase cigarette use, their immediate post-smoking mood stabilizes, with boys showing stabilization in background mood as well.
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  • Low‑Dose Interleukin‑2 Expands Regulatory T Cells and Modulates Biomarkers in Mild–Moderate Alzheimer’s Disease: Phase 2a Randomized Trial Shows Safety and Promising Signals
  • Low‑Dose IL‑2 after Lymphodepletion and TIL Infusion Offers Comparable Immune and Clinical Outcomes to High‑Dose IL‑2 in Metastatic Melanoma
  • History of Thrombosis and Hematologic Disease Double the Risk of New Clots in Persistently aPL‑Positive Patients: Prospective APS ACTION Registry Analysis
  • Can an 11β‑HSD1 Inhibitor Improve Prednisolone’s Benefit–Risk Ratio in Polymyalgia Rheumatica? Early Human Trial Suggests Feasibility
  • Tirzepatide Lowers 10‑Year Predicted Risk of Cardiovascular Disease and Type 2 Diabetes in Adults with Obesity and Prediabetes: Post hoc Analysis of SURMOUNT‑1
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