Specialties – Page 68

Evaluating Cardiovascular-Focused Messaging to Enhance Influenza Vaccination Uptake in Diverse U.S. Populations

By MedXY 10/03/2025

A large randomized trial in the U.S. found no significant improvement in influenza vaccination rates with cardiovascular-focused messaging compared to usual care, despite prior positive findings in Denmark.

Gastroenterology Infectious Diseases news Pediatrics

Revisiting Rehydration Strategies in Severe Acute Malnutrition with Gastroenteritis: Intravenous Versus Oral Approaches

By MedXY 10/03/2025

A recent trial assessing intravenous versus oral rehydration in children with severe acute malnutrition and gastroenteritis found no mortality difference at 96 hours, challenging fears of fluid overload and supporting cautious consideration of intravenous therapy.

Cardiology Clinical Updates news Specialties

Targeting APOC3 with Olezarsen in Moderate Hypertriglyceridemia: Advances in Antisense Therapies for Triglyceride Reduction

By MedXY 10/03/2025

Olezarsen, a GalNAc-conjugated antisense oligonucleotide targeting APOC3 mRNA, significantly reduces triglyceride levels in moderate hypertriglyceridemia, offering a promising therapeutic advance with favorable safety in cardiovascular risk patients.

Cardiology news Public Health

Transforming Hypertension Management: Home-Based Care Success in Rural South Africa

By MedXY 10/03/2025

A randomized trial in rural South Africa showed home-based hypertension care with community health workers and mobile technology significantly lowered systolic blood pressure and improved control versus standard clinic care at 6 and 12 months.

Medical News news Public Health Specialties

Predicting Nobel Laureates: Experts Weigh In on the 2025 Nobel Prize Contenders

By MedXY 10/02/2025

Scientists share insights on leading Nobel Prize contenders like leptin discoverer Jeffrey Friedman, pioneer of protein phase separation Anthony Hyman, and optogenetics innovator Karl Deisseroth ahead of the 2025 announcements.

Gastroenterology news Specialties

Primary Sclerosing Cholangitis in a 45-Year-Old Male: A Case Report

By MedXY 10/02/2025

A 45-year-old male presents with cholestatic liver enzyme elevation and pruritus, diagnosed with primary sclerosing cholangitis confirmed by imaging and liver biopsy. Clinical management and prognosis are discussed.

Clinical Updates news Psychiatry Specialties

Balancing Risks and Benefits: Early Antipsychotic Dose Reduction Versus Maintenance After First-Episode Psychosis Remission

By MedXY 10/01/2025

A randomized clinical trial reveals early dose reduction of antipsychotics after first-episode psychosis remission increases short-term relapse risk and lowers quality of life, but may improve long-term functioning over four years.

Clinical Updates Neurology news Pediatrics Specialties

Memantine Shows Promise for Improving Social Impairment in Youths with Autism Spectrum Disorder

By MedXY 10/01/2025

A 12-week randomized clinical trial demonstrates memantine’s efficacy and safety in improving social impairments in youths with ASD, with elevated pgACC glutamate levels serving as a predictive biomarker for treatment response.

news Pediatrics Specialties

Long-Term Educational Trajectories After Preterm Birth: Unraveling the Roles of Biological and Sociodemographic Factors

By MedXY 10/01/2025

This study reveals that although individuals born preterm face higher risks of lower educational attainment, sociodemographic factors have a greater impact on long-term educational outcomes than prematurity itself.

Clinical Updates news Oncology Specialties

Evaluating the Addition of Polymeric Micellar Paclitaxel to Gemcitabine and Cisplatin in Advanced Biliary Tract Cancer: Insights from a Phase 3 Randomized Clinical Trial

By MedXY 10/01/2025

A South Korean phase 3 trial found that adding polymeric micellar paclitaxel to gemcitabine and cisplatin did not improve survival for advanced biliary tract cancer, highlighting the challenges of intensified chemotherapy regimens.

AI news Pediatrics Specialties

Decoding Nonverbal Learning Disability in Children: Distinct Profiles and Their Clinical Implications

By MedXY 10/01/2025

A cross-sectional study identifies four distinct profiles of nonverbal learning disability (NVLD) in children, revealing significant heterogeneity in visual-spatial deficits, academic skills, and psychiatric diagnoses, highlighting implications for diagnosis and tailored interventions.

Clinical Updates OB/GYN & Women's Health Public Health Specialties

Cost-Effectiveness of Mailed HPV Self-Testing Kits for Cervical Cancer Screening Across Diverse Screening Histories

By MedXY 10/01/2025

Economic evaluation shows direct mailing of HPV self-sampling kits improves cervical cancer screening completion and is cost-effective among varied screening history groups in a US healthcare system, with budget benefits over time.

Clinical Updates news Oncology Specialties

Bridging the Gap: Overcoming Barriers to Timely Melanoma Diagnosis and Treatment in Latino Patients

By MedXY 10/01/2025

This article explores the facilitators and barriers Latino patients face in timely melanoma diagnosis and treatment, highlighting health insurance, linguistic challenges, and patient advocacy as key factors affecting outcomes.

Clinical Updates news Psychiatry Specialties

Heart Rate Variability Biofeedback in Substance Use Disorder: Emerging Evidence from a Randomized Clinical Trial and Contextual Review

By MedXY 10/01/2025

Second-generation heart rate variability biofeedback (HRVB) shows promise in reducing craving, negative affect, and substance use in adults with substance use disorder (SUD), supporting its potential as an adjunctive treatment in early recovery.

Cardiology Clinical Updates Nephrology news Specialties

Sustained Cardiovascular Health in Young Adulthood Significantly Reduces Midlife Cardiovascular and Kidney Risks

By MedXY 10/01/2025

A high cumulative cardiovascular health score from ages 30 to 40 correlates with substantially lower risks of cardiovascular and kidney events in midlife, underscoring the impact of early-life prevention strategies.

Clinical Updates General Surgery news Specialties

Non-β-Lactam Antibiotics, β-Lactam Allergy, and Surgical Site Infections: Implications for Prophylaxis and Stewardship

By MedXY 10/01/2025

This study evaluates how reported β-lactam allergy and choice of prophylactic antibiotics impact surgical site infection rates, revealing non-β-lactam use increases SSI risk while allergy alone does not independently predict infections.

Clinical Updates Oncology Specialties

Deciphering the Role of Intratumoral Microbiota in Breast Cancer: Pathogenesis to Precision Therapeutics

By MedXY 09/30/2025

Intratumoral microbiota significantly influence breast cancer development, progression, and therapeutic response. Their diverse composition across subtypes presents diagnostic and prognostic opportunities. Emerging strategies target these microbes to improve treatment efficacy and overcome resistance.

Clinical Updates Oncology

Novel Heparanase Inhibitor LMW-DSS Shows Promise in Preventing Breast Cancer Metastasis by Targeting Migration and Angiogenesis

By MedXY 09/30/2025

Low-molecular-weight dextran sulfate sodium (LMW-DSS), a new heparanase inhibitor, effectively prevents breast cancer metastasis in mice by inhibiting cancer cell migration and angiogenesis, offering a promising therapeutic approach with minimal bleeding risk.

Clinical Updates Oncology Specialties

Advancing Immunotherapy in Head and Neck Cancer: A Curcumin-Based Polymer Prodrug Nanoplatform Targeting Cancer Stemness and Tumor Microenvironment

By MedXY 09/29/2025

A novel curcumin-based polymer prodrug nanoplatform enhances immunotherapy in head and neck cancer by targeting tumor cell stemness and reversing immunosuppression via synergistic photothermal, photodynamic, and ferroptosis mechanisms.

Neurology Pediatrics Psychiatry Specialties

Unraveling ADHD: Gut Microbial Signatures and the Role of SCFA Deficiency in Symptom Pathogenesis

By MedXY 09/29/2025

Recent research reveals distinct gut microbial and metabolic profiles linked to ADHD symptoms, highlighting short-chain fatty acid deficiency as a key mechanism driving hyperactivity and inattention.