Cardiology – Page 10

Clopidogrel versus Aspirin for Secondary Prevention in Coronary Artery Disease: A Comprehensive Meta-Analysis

By MedXY 10/11/2025

This meta-analysis of nearly 29,000 CAD patients shows clopidogrel monotherapy reduces major cardiovascular events more than aspirin without increasing major bleeding risk, supporting clopidogrel as preferred secondary prevention.

Cardiology news Specialties

Vericiguat in Heart Failure with Reduced Ejection Fraction: Evidence from Pooled Analyses of VICTORIA and VICTOR Trials

By MedXY 10/10/2025

Pooled data from VICTORIA and VICTOR trials demonstrate that vericiguat significantly reduces cardiovascular death and heart failure hospitalization in a wide spectrum of patients with heart failure and reduced ejection fraction, including those without recent worsening, supporting its role as an adjunctive therapy.

Cardiology Clinical Updates news Specialties

Vericiguat in Chronic Heart Failure with Reduced Ejection Fraction: Insights from the VICTOR Phase 3 Trial

By MedXY 10/10/2025

The VICTOR trial evaluated vericiguat in HFrEF patients without recent worsening, showing no significant reduction in composite cardiovascular death or heart failure hospitalization, but fewer cardiovascular and all-cause deaths with acceptable safety.

Cardiology news

Reevaluating New-Onset Atrial Fibrillation After CABG: Insights from Long-Term Continuous Monitoring

By MedXY 10/10/2025

A multicenter prospective study reveals a higher incidence but very low burden of new-onset atrial fibrillation post-CABG, challenging current anticoagulation guidelines.

Cardiology news Oncology

Long-Term Risk Factors for Valvular Heart Disease in Childhood Cancer Survivors: Insights from a European Case-Control Study

By MedXY 10/10/2025

Heart radiation, anthracyclines, and platinum chemotherapy significantly increase the risk of valvular heart disease decades after childhood cancer treatment, highlighting the need for vigilant, lifelong cardiac monitoring in survivors.

Anesthesiology Cardiology news

Acute Normovolemic Hemodilution in Adult Cardiac Surgery: Efficacy, Safety, and Underutilization

By MedXY 10/10/2025

This article reviews a large retrospective study evaluating acute normovolemic hemodilution (ANH) in adult cardiac surgery, demonstrating its association with reduced blood transfusions and cost savings, yet highlighting its underuse in clinical practice.

Cardiology HIV/AIDS news Specialties

Early HIV Treatment and Cardiovascular Health: Insights from the START Study

By MedXY 10/09/2025

Early ART initiation in HIV-positive adults with high CD4+ counts shows no overall cardiovascular benefit, but reduced CVD events in women suggest potential sex-specific effects needing further study.

Cardiology news Pediatrics Public Health Specialties

Trends in Body Composition and Cardiometabolic Risk Factors in Spanish Children Over Three Decades

By MedXY 10/05/2025

This article reviews a 30-year study from Spain analyzing body composition and cardiometabolic risk factors in children aged 8-11, showing obesity plateauing, lipid improvements, blood pressure reductions, but rising insulin levels from 1992 to 2022.

Cardiology Infectious Diseases news

Evaluating Cardiovascular-Focused Messaging to Enhance Influenza Vaccination Uptake in Diverse U.S. Populations

By MedXY 10/03/2025

A large randomized trial in the U.S. found no significant improvement in influenza vaccination rates with cardiovascular-focused messaging compared to usual care, despite prior positive findings in Denmark.

Cardiology Clinical Updates news Specialties

Targeting APOC3 with Olezarsen in Moderate Hypertriglyceridemia: Advances in Antisense Therapies for Triglyceride Reduction

By MedXY 10/03/2025

Olezarsen, a GalNAc-conjugated antisense oligonucleotide targeting APOC3 mRNA, significantly reduces triglyceride levels in moderate hypertriglyceridemia, offering a promising therapeutic advance with favorable safety in cardiovascular risk patients.

Cardiology news Public Health

Transforming Hypertension Management: Home-Based Care Success in Rural South Africa

By MedXY 10/03/2025

A randomized trial in rural South Africa showed home-based hypertension care with community health workers and mobile technology significantly lowered systolic blood pressure and improved control versus standard clinic care at 6 and 12 months.

Cardiology Clinical Updates Nephrology news Specialties

Sustained Cardiovascular Health in Young Adulthood Significantly Reduces Midlife Cardiovascular and Kidney Risks

By MedXY 10/01/2025

A high cumulative cardiovascular health score from ages 30 to 40 correlates with substantially lower risks of cardiovascular and kidney events in midlife, underscoring the impact of early-life prevention strategies.

Cardiology Clinical Updates Nephrology

Exploring the Impact of Reduced Left Ventricular Function on Outcomes After PCI in Chronic Kidney Disease Patients

By MedXY 09/27/2025

Reduced left ventricular ejection fraction (LVEF) adversely affects survival and myocardial infarction risk in patients with chronic kidney disease undergoing percutaneous coronary intervention, despite no significant difference in overall major cardiovascular events.

Cardiology Clinical Updates General Surgery Pathology & Lab Medicine Specialties

Circulating Trimethylamine N-Oxide: A Novel Biomarker for Predicting Abdominal Aortic Aneurysm Progression and Surgical Risk

By MedXY 09/27/2025

Elevated plasma TMAO levels are associated with higher risk of abdominal aortic aneurysm development, rapid aneurysm growth, and need for surgical repair, providing a promising tool for risk stratification and personalized surveillance.

AI Cardiology Specialties

Harnessing Artificial Intelligence for Enhanced Prediction of Complete Heart Block Risk via Electrocardiography

By MedXY 09/27/2025

AIRE-CHB, a novel AI-enhanced ECG model, significantly improves prediction of incident complete heart block, outperforming traditional bifascicular block assessment and offering promising clinical utility in risk stratification and management.

Cardiology news

Long-Term Survival Outcomes After Initial Stress Testing Versus Coronary CTA in Suspected CAD: Insights from the PROMISE Trial

By MedXY 09/27/2025

The PROMISE trial's 10-year follow-up shows no difference in all-cause or cardiovascular mortality between initial functional stress testing and anatomic coronary CTA in symptomatic patients with suspected coronary artery disease.

Cardiology

Sustained Benefits of Physiology-Guided Complete Revascularization in Elderly Myocardial Infarction Patients: Insights from the FIRE Trial Three-Year Follow-Up

By MedXY 09/27/2025

The FIRE randomized clinical trial demonstrates that physiology-guided complete revascularization in patients aged 75 and older with myocardial infarction and multivessel disease maintains significant reductions in death, MI, stroke, and heart failure hospitalizations over a three-year follow-up, outperforming culprit-only treatment.

Cardiology Public Health Specialties

High-Dose vs Standard-Dose Influenza Vaccine and Cardiovascular Outcomes in Older Adults: Insights from the DANFLU-2 Randomized Clinical Trial and Related Evidence

By MedXY 09/27/2025

This review synthesizes evidence on high-dose versus standard-dose influenza vaccines for cardiovascular outcomes in older adults, focusing on the large DANFLU-2 trial and complementary studies, highlighting modest cardiovascular benefits and implications for clinical practice.

Cardiology Nephrology

Abelacimab Shows Consistent Bleeding Safety Across Kidney Function in Atrial Fibrillation: Insights from the AZALEA-TIMI 71 Trial

By MedXY 09/27/2025

This analysis of the AZALEA-TIMI 71 trial reveals that abelacimab, a novel factor XI inhibitor, significantly reduces bleeding risk versus rivaroxaban in atrial fibrillation patients, regardless of kidney function, suggesting its promise for those with chronic kidney disease.

Cardiology news Specialties

High Prevalence and Clinical Impact of Sleep Apnea in Hypertrophic Cardiomyopathy: Insights from a Prospective Cohort Study

By MedXY 09/27/2025

Sleep disordered breathing affects over half of patients with hypertrophic cardiomyopathy, correlating with worsening myocardial remodeling, diastolic dysfunction, and subclinical myocardial injury, underscoring the need for clinical trials on intervention.