Cardiorespiratory Exercise Enhances Cognitive Function After Ischemic Stroke: Insights from the PISCES-ZODIAC Trial

Cardiorespiratory Exercise Enhances Cognitive Function After Ischemic Stroke: Insights from the PISCES-ZODIAC Trial

An 8-week cardiorespiratory exercise program initiated 2 months after ischemic stroke improved cognitive performance at 12 months, despite no significant preservation of hippocampal volume compared with control. The intervention was safe and feasible, offering promising avenues for poststroke cognitive care.
Fertility-Preserving Hormonal Therapy vs Hysterectomy in Early-Stage Endometrial Cancer: Survival Outcomes and Clinical Implications

Fertility-Preserving Hormonal Therapy vs Hysterectomy in Early-Stage Endometrial Cancer: Survival Outcomes and Clinical Implications

This analysis compares survival in young women with early-stage endometrial cancer treated with fertility-preserving hormonal therapy versus hysterectomy, highlighting survival equivalence in women under 40 years and increased mortality risk in older patients undergoing hormonal therapy.
Precision Psychiatry Roadmap: Integrating Biology into Mental Disorder Classification and Treatment

Precision Psychiatry Roadmap: Integrating Biology into Mental Disorder Classification and Treatment

Mental disorders currently diagnosed symptomatically can be redefined using biology-informed frameworks integrating biological, behavioral, and environmental data. The Precision Psychiatry Roadmap aims to harmonize global research and clinical efforts to improve diagnostics and develop mechanism-based treatments.