GLIAA Trial Results: Contrast-Enhanced MRI Remains the Gold Standard for Re-irradiation Planning in Recurrent Glioblastoma
Posted innews Oncology Radiology

GLIAA Trial Results: Contrast-Enhanced MRI Remains the Gold Standard for Re-irradiation Planning in Recurrent Glioblastoma

The multicenter GLIAA trial demonstrated that FET-PET-guided target volume delineation for re-irradiation does not provide a progression-free survival benefit over standard contrast-enhanced T1-weighted MRI in patients with recurrent glioblastoma, solidifying MRI's role as the preferred clinical delineation method.
The Earlier, the Better: INTERACT Pooled Analysis Confirms 3-Hour Golden Window for Intensive Blood Pressure Lowering in Acute ICH
Posted inEmergency Medicine Neurology news

The Earlier, the Better: INTERACT Pooled Analysis Confirms 3-Hour Golden Window for Intensive Blood Pressure Lowering in Acute ICH

A pooled analysis of over 11,000 patients from the INTERACT trials demonstrates that intensive blood pressure reduction significantly improves functional recovery in acute intracerebral hemorrhage, with the most robust benefits observed when treatment is initiated within three hours of symptom onset.
Smartphone-Based Pulmonary Rehabilitation Bridging the Gap in Chronic Respiratory Care: A Randomized Controlled and Feasibility Study
Posted inFamily Medicine & Nutrition news Respiratory

Smartphone-Based Pulmonary Rehabilitation Bridging the Gap in Chronic Respiratory Care: A Randomized Controlled and Feasibility Study

A randomized trial demonstrates that a smartphone app-based pulmonary rehabilitation program significantly improves quality of life and physical activity in patients with chronic respiratory diseases, offering a scalable alternative to traditional center-based care despite challenges in patient adherence.
Telemedicine is Superior to Onboard Neurologists for Optimizing Mobile Stroke Unit Efficiency: Results from the MSU-TELEMED Trial
Posted inEmergency Medicine Neurology news

Telemedicine is Superior to Onboard Neurologists for Optimizing Mobile Stroke Unit Efficiency: Results from the MSU-TELEMED Trial

The MSU-TELEMED trial demonstrates that a telemedicine model for mobile stroke units significantly improves neurologist resource utilization while maintaining safety, outperforming the traditional onboard neurologist model in a hierarchical composite outcome despite a minor four-minute treatment decision delay.
Bridging the Care Gap: Smartphone-Based Pulmonary Rehabilitation Enhances Quality of Life and Physical Activity in Chronic Respiratory Disease
Posted inInternal Medicine news Respiratory

Bridging the Care Gap: Smartphone-Based Pulmonary Rehabilitation Enhances Quality of Life and Physical Activity in Chronic Respiratory Disease

A 12-week randomized controlled trial reveals that smartphone-based pulmonary rehabilitation significantly improves quality of life and physical activity in patients with chronic respiratory diseases, offering a scalable and feasible alternative to traditional center-based programs despite challenges in long-term adherence.
Individualized Feedback Letters Fail to Reduce Long-Term Alcohol Consumption: Insights from a 4-Year RCT
Posted innews Psychiatry Public Health

Individualized Feedback Letters Fail to Reduce Long-Term Alcohol Consumption: Insights from a 4-Year RCT

A 4-year randomized controlled trial found that computer-generated feedback letters failed to reduce alcohol consumption in the general population. Unexpectedly, the control group showed greater reduction at 48 months, suggesting that current digital intervention strategies may require significant adaptation for low-risk drinkers.