Nature: Influenza and SARS‑CoV‑2 can awaken dormant breast cancer cells and trigger lung metastasis
Posted inClinical Updates Infectious Diseases news Oncology Specialties

Nature: Influenza and SARS‑CoV‑2 can awaken dormant breast cancer cells and trigger lung metastasis

A Nature paper shows influenza and SARS‑CoV‑2 lung infections can reactivate dormant disseminated breast cancer cells (DCCs) via IL‑6 and CD4+ T‑cell–mediated mechanisms, with concordant human data linking SARS‑CoV‑2 infection to higher cancer‑related mortality and pulmonary metastasis risk.
Metformin and ‘Anti‑Aging’: Promising Mechanisms but Mixed Clinical Evidence — What Recent Trials Tell Us
Posted inClinical Updates Family Medicine & Nutrition Internal Medicine news Specialties

Metformin and ‘Anti‑Aging’: Promising Mechanisms but Mixed Clinical Evidence — What Recent Trials Tell Us

Recent randomized and mechanistic studies provide a nuanced view: metformin shows plausible anti‑aging mechanisms and microbiome‑linked cognitive associations, but randomized trials report no clear anti‑cancer or anti‑senescence effects in humans to date.