Revealing Metabolic Subtypes in Gestational Diabetes Using Dynamic OGTT-Derived C-Peptide Trajectories: Implications for Personalized Risk and Management
Posted inClinical Updates Diabetes & Endocrinology news OB/GYN & Women's Health Specialties

Revealing Metabolic Subtypes in Gestational Diabetes Using Dynamic OGTT-Derived C-Peptide Trajectories: Implications for Personalized Risk and Management

Dynamic C-peptide patterns during OGTT uncover metabolic heterogeneity in GDM, identifying insulin-resistant women at risk for fetal overgrowth and normoglycemic women at risk for preeclampsia, suggesting improved stratified treatment beyond glucose-based diagnosis.
Prenatal Exposure to Chlorpyrifos and Its Long-Term Impact on Brain Development and Motor Function in Children: Evidence from Imaging and Cohort Studies
Posted inClinical Updates Neurology news OB/GYN & Women's Health Pediatrics Specialties

Prenatal Exposure to Chlorpyrifos and Its Long-Term Impact on Brain Development and Motor Function in Children: Evidence from Imaging and Cohort Studies

Elevated prenatal chlorpyrifos exposure is linked to widespread brain structural abnormalities, reduced neuronal density, and impaired motor functions in children, underscoring the need for exposure minimization during pregnancy.
Global Impact of Cardiovascular Risk Factors on Lifetime Cardiovascular Disease Burden and Mortality: A Comprehensive Evidence Synthesis
Posted inCardiology Clinical Updates news Public Health Specialties

Global Impact of Cardiovascular Risk Factors on Lifetime Cardiovascular Disease Burden and Mortality: A Comprehensive Evidence Synthesis

This review integrates data from over two million individuals globally, showing that absence of five key cardiovascular risk factors at age 50 confers a life expectancy advantage exceeding a decade, with midlife modification of hypertension and smoking yielding substantial gains in disease-free survival and overall longevity.
Modern Pain Neuroscience Approach Versus Usual Care in Chronic Whiplash Disorders: Evidence from a Randomized Clinical Trial
Posted inClinical Updates Neurology news Orthopedics Specialties

Modern Pain Neuroscience Approach Versus Usual Care in Chronic Whiplash Disorders: Evidence from a Randomized Clinical Trial

This review analyzes a randomized clinical trial comparing modern pain neuroscience approach and usual care physiotherapy in chronic whiplash disorders, highlighting immediate and 12-month improvements, cost-effectiveness, and benefits in anxiety and central sensitization symptoms with MPNA.
Synergistic Impact of Probiotic and Omega-3 Supplementation Combined with Ultra-Short Race Pace Training on Sprint Swimming Performance
Posted inClinical Updates Family Medicine & Nutrition Internal Medicine news Specialties

Synergistic Impact of Probiotic and Omega-3 Supplementation Combined with Ultra-Short Race Pace Training on Sprint Swimming Performance

Combining probiotics and omega-3 supplementation with ultra-short race pace training significantly enhances sprint swimming performance by improving anaerobic capacity, neuromuscular function, and body composition in competitive male swimmers.
Exploring Over-the-Counter Herbal and Nutritional Products for Adult Depression: A Comprehensive Evidence Landscape
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Exploring Over-the-Counter Herbal and Nutritional Products for Adult Depression: A Comprehensive Evidence Landscape

A scoping review of 209 trials reveals a concentrated evidence base for omega-3s, St John’s Wort, saffron, probiotics, and vitamin D in treating adult depression, highlights promising but under-researched herbal and supplement candidates, and underscores the need for improved safety reporting and integrative therapy evaluations.