Efficacy and Safety of High-Dose Versus Low-Dose Primaquine for Plasmodium vivax in Cambodia: A Randomised Controlled Trial
A Cambodian study shows that a 14-day high-dose primaquine regimen (7.0 mg/kg) significantly reduces Plasmodium vivax relapse compared to the standard low-dose (3.5 mg/kg), with comparable safety in G6PD-normal patients.