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Innovative Immunotherapy Combines to Transform Treatment of HER2-Expressing Advanced Urothelial Cancer
Posted inOncology Urology

Innovative Immunotherapy Combines to Transform Treatment of HER2-Expressing Advanced Urothelial Cancer

Posted by By MedXY 10/25/2025
This study demonstrates that disitamab vedotin plus toripalimab significantly improves survival outcomes over chemotherapy in untreated HER2-positive advanced urothelial cancer.
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Prognostic Role of HER2 Amplification and Mutations in Metastatic Colorectal Cancer: Insights from Eight Randomized Trials
Posted inClinical Updates news Oncology Specialties

Prognostic Role of HER2 Amplification and Mutations in Metastatic Colorectal Cancer: Insights from Eight Randomized Trials

Posted by By MedXY 09/10/2025
HER2 amplification/mutation in RAS/BRAF wild-type metastatic colorectal cancer is a negative prognostic factor but does not predict differential benefit from bevacizumab or anti-EGFR therapies, based on analysis of 1,604 patients across eight randomized trials.
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  • Delayed Immunity to Streptococcus pyogenes and Respiratory Viruses in Young Children Following COVID-19 Restrictions: Implications for Recent Infection Surges
  • Declining Antiviral Prescribing for High-Risk Children with Influenza in US Pediatric Emergency Departments During the COVID-19 Era
  • Glucagon-Like Peptide-1 Receptor Agonists May Lower the Risk of Nonexudative Age-Related Macular Degeneration in Obese Non-Diabetic Adults
  • Early Diagnosis of Postpartum Haemorrhage: Insights from the E-MOTIVE Trial in Africa
  • Oral Manifestations of Lamellar Ichthyosis: A Case Report of Two Siblings
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