Oncology – Page 8

AI Foundation Model Revolutionizes Non-Invasive Diagnosis and Grading of Prostate Cancer

By MedXY 09/03/2025

A multidisciplinary Chinese team has developed an AI-driven MRI-pathology foundation model that enables accurate, non-invasive diagnosis and grading of prostate cancer, significantly improving clinical decision-making and reducing unnecessary biopsies.

Gastroenterology news Oncology Specialties

From Silent Struggles to Serious Threats: Understanding Your Liver’s Journey from Hepatitis to Cancer

By MedXY 09/03/2025

Explore how subtle liver symptoms can signal serious illness, the progression from hepatitis to liver cancer, and effective habits to protect your liver health.

Clinical Updates news Oncology

Distinct Clinical and Genomic Profiles of Anogenital Basal Cell Carcinomas Highlight Higher Recurrence Risks

By MedXY 09/01/2025

Anogenital basal cell carcinomas (BCCs) represent a rare subtype with unique genomic features and a higher recurrence rate compared to UV-related BCCs. This French cohort study elucidates their clinical characteristics, lichen sclerosus association, and dependence on the sonic hedgehog pathway, informing tailored management strategies.

Clinical Updates OB/GYN & Women's Health Oncology Specialties

Everolimus Plus Carboplatin: A Promising Combination for Advanced Triple-Negative Breast Cancer

By MedXY 09/01/2025

A phase 2 study shows adding everolimus to carboplatin significantly improves progression-free survival in advanced TNBC with manageable safety profile, indicating a potential new treatment avenue.

news Oncology Specialties

Targeting Oxytocin Receptor: A Novel Strategy Against Hepatocellular Carcinoma Using Atosiban

By MedXY 08/31/2025

Recent research identifies the oxytocin receptor (OXTR) as a critical driver of liver cancer via Hippo/YAP signaling. The FDA-approved tocolytic drug Atosiban shows promise in blocking this pathway, offering new therapeutic avenues in hepatocellular carcinoma management.

news OB/GYN & Women's Health Oncology Specialties

Age-Dependent Survival Outcomes in Early-Stage Endometrial Cancer: Fertility-Preserving Hormonal Therapy Versus Hysterectomy

By MedXY 08/31/2025

Fertility-preserving hormonal therapy for early-stage endometrial cancer shows comparable 5-year survival to hysterectomy in women under 40, but a significantly higher mortality risk in those aged 40-49 years, highlighting age as a critical factor in treatment decisions.

news Oncology Pathology & Lab Medicine Specialties

Decoding Cancer Risk: Rare Pathogenic Variants and Their Role in Single and Multiple Cancer Diagnoses

By MedXY 08/31/2025

A large population-based genetic study clarifies the associations of rare pathogenic variants in established cancer predisposition genes with the risk of single and multiple primary cancers, supporting multigene panel testing in affected individuals.

news OB/GYN & Women's Health Oncology Specialties

Fertility-Preserving Hormonal Therapy vs Hysterectomy in Early-Stage Endometrial Cancer: Survival Outcomes and Clinical Implications

By MedXY 08/31/2025

This analysis compares survival in young women with early-stage endometrial cancer treated with fertility-preserving hormonal therapy versus hysterectomy, highlighting survival equivalence in women under 40 years and increased mortality risk in older patients undergoing hormonal therapy.

Medical News news Oncology Public Health Specialties

Persistent Medical Debt After Cancer Diagnosis: Insights from a Large Massachusetts Cohort Study

By MedXY 08/30/2025

A Massachusetts cohort study reveals modest but persistent increases in medical debt after cancer diagnosis, particularly in colorectal and bladder cancers, despite high insurance coverage. Total debt, bankruptcy rates, and credit scores remained largely unchanged in the overall population.

Allergy & Immunology Clinical Updates news Oncology Specialties

Tumor Microenvironment-Responsive Mn-Based Nanoplatform Activates cGAS-STING Pathway Coupled with Metabolic Interference for Enhanced Antitumor Therapy

By MedXY 08/30/2025

A novel Mn-based nanoplatform, LT@MnO@MON-HA (LMMH), responsive to tumor microenvironment triggers metabolic disruption and robust cGAS-STING activation, potentiating chemodynamic therapy and immunotherapy for improved tumor suppression.

Clinical Updates news Oncology Radiology Specialties

Real-time MRI Visualization of Tumor Acidosis: A Novel Predictor of Therapeutic Efficacy Using a Manganese Sulfide-Based Nanoplatform

By MedXY 08/30/2025

A manganese sulfide nanoplatform loaded with proton pump inhibitor enables real-time MRI visualization of tumor acidosis, providing early prediction of therapeutic efficacy and potential for improved cancer management.

Allergy & Immunology Clinical Updates news Oncology Specialties

Manganese: A Potent Catalyst Enhancing Cancer Immunotherapy

By MedXY 08/30/2025

Manganese and its nanoparticles play a pivotal role in cancer immunotherapy by modulating immune pathways, reshaping the tumor microenvironment, and serving as effective adjuvants and drug carriers, offering promising avenues to overcome current therapeutic challenges.

OB/GYN & Women's Health Oncology Specialties

ChatGPT-4o versus Gynecologic Oncologists in Endometrial Cancer Patient Communication: A Prospective Comparative Study

By MedXY 08/27/2025

This study compares ChatGPT-4o and gynecologic oncologists in addressing endometrial cancer patient questions, showing superior AI accuracy, empathy, and completeness, though lengthy responses may challenge patient comprehension.

Anesthesiology General Surgery news Nursing & care Oncology Specialties

Electroacupuncture Significantly Shortens Postoperative Ileus After Laparoscopic Gastrectomy for Gastric Cancer: Insights from a Multicenter Randomized Trial

By MedXY 08/26/2025

This multicenter randomized trial demonstrates that electroacupuncture reduces postoperative ileus duration and accelerates gastrointestinal recovery after laparoscopic gastrectomy for gastric cancer, outperforming sham and standard care.

Clinical Updates news Oncology Radiology Specialties

Optimizing Twice-Daily Thoracic Radiotherapy Dosage in Limited-Stage Small-Cell Lung Cancer: Impact on Survival and Toxicity

By MedXY 08/26/2025

A phase II trial reveals that high-dose twice-daily thoracic radiotherapy (60 Gy/40 fractions) significantly improves survival without increasing severe toxicity compared to the standard dose (45 Gy/30 fractions) in limited-stage SCLC patients.

Oncology Specialties

Extended Rivaroxaban Therapy in Cancer Patients with Low-Risk Pulmonary Embolism: 6 OR 18 Months？

By MedXY 08/26/2025

An 18-month course of rivaroxaban significantly lowers recurrent venous thromboembolism compared to 6 months in cancer patients with low-risk pulmonary embolism without a substantial increase in major bleeding risk.

Oncology Specialties

Anticoagulant therapy for cancer-associated splanchnic vein thrombosis: Outcomes during a one-year follow-up period

By MedXY 08/26/2025

This study evaluates one-year outcomes in cancer-associated splanchnic vein thrombosis, showing anticoagulation increases recanalization and bleeding risk but offers no survival benefit, highlighting tumor thrombus and metastasis as key mortality predictors.

Oncology Psychiatry Specialties

Reducing Carcinogen Exposure in Smokers with Serious Mental Illness: Insights from a Randomized Controlled Trial of E-Cigarette Provision

By MedXY 08/25/2025

This RCT demonstrates that disposable e-cigarettes significantly reduce carcinogen levels short-term among smokers with serious mental illness, underscoring the need for behavioral support to sustain harm reduction.

Oncology Psychiatry Specialties

Esketamine in Lung Cancer Patients with Major Depression: Efficacy for Smoking Cessation and Treatment-Resistant Depression

By MedXY 08/25/2025

This review synthesizes evidence from a randomized trial and real-world studies showing esketamine's efficacy and safety in smoking cessation among lung cancer patients with MDD, as well as in treatment-resistant depression, highlighting cognitive benefits and long-term safety.

news Oncology Public Health Specialties

International Trends in Biliary Tract Cancer Mortality from 2000 to 2022: A Comprehensive WHO Database Analysis

By MedXY 08/25/2025

This observational study reveals stable global biliary tract cancer mortality rates over two decades, with a striking rise in intrahepatic cholangiocarcinoma mortality, underscoring the need for targeted screening and management strategies.