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Declining Vaccination Rates Among US Kindergarteners: A Growing Public Health Concern
Posted inMedical News Wellness & Lifestyle

Declining Vaccination Rates Among US Kindergarteners: A Growing Public Health Concern

Posted by By MedXY 08/02/2025
Vaccination rates for US kindergarteners have declined for the third consecutive year, raising public health concerns. Experts attribute this trend to increased vaccine hesitancy and misinformation.
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Interval Colorectal Cancer Risk and Outcomes after Positive FIT with Follow-Up Colonoscopy in Taiwan Screening Program
Posted inClinical Updates Medical News

Interval Colorectal Cancer Risk and Outcomes after Positive FIT with Follow-Up Colonoscopy in Taiwan Screening Program

Posted by By MedXY 08/01/2025
A Taiwanese cohort study reveals higher interval colorectal cancer incidence and mortality after follow-up colonoscopy for positive FIT compared to negative FIT, highlighting risk stratification and adenoma detection rate impact on outcomes.
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Lipoprotein(a) as an Independent Predictor of Peripheral Artery Disease and Carotid Stenosis: Insights from a Large UK Biobank Study
Posted inClinical Updates Medical News

Lipoprotein(a) as an Independent Predictor of Peripheral Artery Disease and Carotid Stenosis: Insights from a Large UK Biobank Study

Posted by By MedXY 08/01/2025
A landmark UK Biobank study demonstrates that elevated lipoprotein(a) independently predicts both the onset and progression of peripheral artery disease and carotid stenosis, beyond traditional cardiovascular risk factors.
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Long-Term Outcomes of Cilta-Cel CAR-T Therapy in Relapsed/Refractory Multiple Myeloma: Five-Year Remission Achieved in One-Third of Patients
Posted inClinical Updates Medical News

Long-Term Outcomes of Cilta-Cel CAR-T Therapy in Relapsed/Refractory Multiple Myeloma: Five-Year Remission Achieved in One-Third of Patients

Posted by By MedXY 08/01/2025
A recent J Clin Oncol study shows that nearly 33% of RRMM patients treated with cilta-cel achieved ≥5 years of progression-free survival, highlighting durable responses and promising biomarkers.
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Efruxifermin for Compensated Liver Cirrhosis in MASH: Phase 2b Results and Clinical Implications
Posted inClinical Updates Medical News

Efruxifermin for Compensated Liver Cirrhosis in MASH: Phase 2b Results and Clinical Implications

Posted by By MedXY 08/01/2025
A phase 2b trial found that efruxifermin did not significantly improve fibrosis at 36 weeks in patients with compensated cirrhosis due to MASH, though longer-term benefit was suggested at 96 weeks.
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Mass Ivermectin Administration for Malaria Control: Translational Insights from Recent Cluster-Randomized Trials
Posted inClinical Updates Medical News

Mass Ivermectin Administration for Malaria Control: Translational Insights from Recent Cluster-Randomized Trials

Posted by By MedXY 07/31/2025
Recent cluster-randomized trials in Kenya and Burkina Faso provide mixed but informative evidence on the efficacy and safety of mass ivermectin administration for malaria control, highlighting both its potential and limitations.
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Mitochondrial Donation and Preimplantation Genetic Testing: Innovations in Reducing mtDNA Disease Transmission
Posted inClinical Updates Medical News

Mitochondrial Donation and Preimplantation Genetic Testing: Innovations in Reducing mtDNA Disease Transmission

Posted by By MedXY 07/31/2025
Mitochondrial donation by pronuclear transfer and preimplantation genetic testing effectively reduce transmission of pathogenic mtDNA variants, offering hope for families at risk of mitochondrial diseases.
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MRD-Guided Consolidation Therapy in Newly Diagnosed Multiple Myeloma: Insights from the MIDAS Phase 3 Trial
Posted inClinical Updates Medical News

MRD-Guided Consolidation Therapy in Newly Diagnosed Multiple Myeloma: Insights from the MIDAS Phase 3 Trial

Posted by By MedXY 07/31/2025
MRD-guided consolidation strategies in transplant-eligible multiple myeloma patients did not significantly improve deep remission rates over conventional approaches, questioning the clinical utility of MRD-adapted intensification.
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Advances in Obesity and Diabetes Management: Highlights from ADA 2025
Posted inClinical Updates Medical News Wellness & Lifestyle

Advances in Obesity and Diabetes Management: Highlights from ADA 2025

Posted by By MedXY 07/31/2025
New weight-loss drug combinations, oral semaglutide cardiovascular outcomes, inhaled insulin for type 1 diabetes, and benefits of switching from diet drinks to water were key ADA 2025 findings.
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FDA Approves Lenacapavir: A Twice-Yearly Injectable PrEP Transforming HIV Prevention
Posted inMedical News Wellness & Lifestyle

FDA Approves Lenacapavir: A Twice-Yearly Injectable PrEP Transforming HIV Prevention

Posted by By MedXY 07/31/2025
Lenacapavir (Yeztugo) becomes the first FDA-approved, twice-yearly injectable PrEP, offering robust long-acting HIV prevention and addressing key adherence barriers.
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Walking More Than 100 Minutes Daily May Lower Risk of Chronic Low Back Pain
Posted inMedical News Wellness & Lifestyle

Walking More Than 100 Minutes Daily May Lower Risk of Chronic Low Back Pain

Posted by By MedXY 07/31/2025
A large prospective cohort study links daily walking of over 100 minutes to reduced risk of chronic low back pain, emphasizing walking volume over intensity as a preventive strategy.
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Sharp Rise in Advanced Alcohol-Related Liver Disease Despite Stable Drinking Rates: Changing Population Risks Highlighted by US Data
Posted inMedical News Wellness & Lifestyle

Sharp Rise in Advanced Alcohol-Related Liver Disease Despite Stable Drinking Rates: Changing Population Risks Highlighted by US Data

Posted by By MedXY 07/31/2025
A twofold rise in advanced liver fibrosis among US heavy drinkers over two decades is linked to increased metabolic syndrome, age, and socioeconomic risk, not higher alcohol intake.
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Benzene in Acne Products: Clinical Implications, Risks, and Regulatory Response
Posted inMedical News Wellness & Lifestyle

Benzene in Acne Products: Clinical Implications, Risks, and Regulatory Response

Posted by By MedXY 07/31/2025
Recent findings of benzene in benzoyl peroxide acne products have sparked debate, recalls, and regulatory scrutiny, prompting calls for improved safety measures despite the continued clinical utility of these therapies.
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Aluminum-Adjuvanted Vaccines in Early Childhood and Risk of Chronic Autoimmune, Allergic, and Neurodevelopmental Disorders: Insights from a Danish Nationwide Cohort Study
Posted inClinical Updates Medical News

Aluminum-Adjuvanted Vaccines in Early Childhood and Risk of Chronic Autoimmune, Allergic, and Neurodevelopmental Disorders: Insights from a Danish Nationwide Cohort Study

Posted by By MedXY 07/31/2025
A comprehensive Danish cohort study finds no evidence linking early childhood aluminum-adsorbed vaccines to increased risks of autoimmune, allergic, or neurodevelopmental disorders, supporting vaccine safety.
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Medial Opening Wedge High Tibial Osteotomy for Medial Compartment Knee Osteoarthritis: Evidence from a Randomized Controlled Trial
Posted inClinical Updates Medical News

Medial Opening Wedge High Tibial Osteotomy for Medial Compartment Knee Osteoarthritis: Evidence from a Randomized Controlled Trial

Posted by By MedXY 07/31/2025
A randomized trial demonstrates that medial opening wedge high tibial osteotomy (HTO) slows cartilage loss and improves symptoms in patients with medial compartment knee osteoarthritis and varus alignment, supporting its role as a joint-preserving intervention.
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Obesity-Linked Liver Cancer: A Preventable Crisis on the Rise
Posted inMedical News Wellness & Lifestyle

Obesity-Linked Liver Cancer: A Preventable Crisis on the Rise

Posted by By MedXY 07/31/2025
Over 60% of liver cancer cases are preventable, yet rising obesity and metabolic dysfunction threaten progress. The Lancet Commission outlines urgent strategies to curb a projected doubling of global liver cancer burden by 2050.
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Preterm Birth Linked to Long-Term Adult Cardiometabolic and Mental Health Risks: New U.S. Cohort Study
Posted inMedical News Wellness & Lifestyle

Preterm Birth Linked to Long-Term Adult Cardiometabolic and Mental Health Risks: New U.S. Cohort Study

Posted by By MedXY 07/30/2025
Adults born preterm face significantly higher risks of cardiometabolic abnormalities and internalizing mental health problems by age 35, according to a new U.S. cohort study.
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Understanding Adult Responses to Cannabis Health Warnings in US Recreational States: Insights from the EPPM Model
Posted inMedical News Wellness & Lifestyle

Understanding Adult Responses to Cannabis Health Warnings in US Recreational States: Insights from the EPPM Model

Posted by By MedXY 07/30/2025
A recent study reveals that most adults in US recreational states respond maladaptively to cannabis health warnings, highlighting challenges and opportunities for improved public health messaging.
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FDA Approves Sephience: A New Oral Therapy for Phenylketonuria
Posted inMedical News

FDA Approves Sephience: A New Oral Therapy for Phenylketonuria

Posted by By MedXY 07/30/2025
The FDA has approved Sephience, an oral therapy for phenylketonuria (PKU), offering a novel treatment option for both children and adults with this rare metabolic disorder.
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Legacy of Leaded Gasoline: New Evidence Links Childhood and Adult Exposure to Cognitive Impairment in Older Adults
Posted inMedical News Wellness & Lifestyle

Legacy of Leaded Gasoline: New Evidence Links Childhood and Adult Exposure to Cognitive Impairment in Older Adults

Posted by By MedXY 07/30/2025
Recent studies confirm that both childhood and adult lead exposure, especially from gasoline and industrial sources, are associated with increased risk for cognitive decline and dementia in later life.
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CDC Retracts Universal COVID-19 Vaccination Recommendation for Pregnancy: Clinical Context, Evidence, and Implications
Posted inMedical News Wellness & Lifestyle

CDC Retracts Universal COVID-19 Vaccination Recommendation for Pregnancy: Clinical Context, Evidence, and Implications

Posted by By MedXY 07/30/2025
The CDC no longer universally recommends COVID-19 vaccination during pregnancy, prompting debate among clinicians as the FDA shifts vaccine composition to target the JN.1 variant. This article analyzes the evidence, rationale, and clinical implications.
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Is There a Norovirus Vaccine on the Horizon? Scientific Progress, Challenges, and Future Directions
Posted inMedical News Wellness & Lifestyle

Is There a Norovirus Vaccine on the Horizon? Scientific Progress, Challenges, and Future Directions

Posted by By MedXY 07/30/2025
Norovirus vaccines show promise in clinical trials, but scientific and logistical challenges remain. No approved vaccine exists yet, though novel approaches, including oral pills, are advancing development.
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Influenza-Associated Acute Necrotizing Encephalopathy in US Children
Posted inClinical Updates Medical News

Influenza-Associated Acute Necrotizing Encephalopathy in US Children

Posted by By MedXY 07/30/2025
A multicenter US study highlights the devastating burden of influenza-associated acute necrotizing encephalopathy in children, with high mortality and disability rates despite aggressive therapy, underscoring the urgent need for prevention and standardized management.
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Systemic Bias in AI: A Double-Edged Sword for Hospital Diagnostic Accuracy
Posted inMedical News Wellness & Lifestyle

Systemic Bias in AI: A Double-Edged Sword for Hospital Diagnostic Accuracy

Posted by By MedXY 07/30/2025
Systemically biased AI models can reduce clinicians' diagnostic accuracy, and explanations alone may not mitigate this harm, according to a multicenter study involving over 450 clinicians.
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Posted inMedical News

Johns Hopkins Hospital Leads U.S. News Rheumatology Rankings

Posted by By Dr.Paul 07/30/2025
Highlight Johns Hopkins Hospital is ranked as the best hospital for rheumatology for the 8th…
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Top U.S. Hospitals for Gastroenterology and GI Surgery: 2025-2026 Rankings and Clinical Implications
Posted inMedical News Wellness & Lifestyle

Top U.S. Hospitals for Gastroenterology and GI Surgery: 2025-2026 Rankings and Clinical Implications

Posted by By MedXY 07/30/2025
Mayo Clinic leads U.S. News' 2025-2026 rankings for gastroenterology and GI surgery, reflecting excellence in outcomes, capabilities, and research. This review examines the clinical context, ranking methodology, and relevance for clinicians and patients.
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Top U.S. Hospitals for Diabetes and Endocrinology: Interpreting the 2025–2026 U.S. News Rankings
Posted inMedical News Wellness & Lifestyle

Top U.S. Hospitals for Diabetes and Endocrinology: Interpreting the 2025–2026 U.S. News Rankings

Posted by By MedXY 07/30/2025
A critical analysis of the 2025–2026 U.S. News rankings for diabetes and endocrinology care, examining methodology, clinical impact, and implications for patient care and referral.
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Redefining Obesity: Impact of the ‘Clinical Obesity’ Framework on Global Prevalence Estimates
Posted inMedical News Wellness & Lifestyle

Redefining Obesity: Impact of the ‘Clinical Obesity’ Framework on Global Prevalence Estimates

Posted by By MedXY 07/30/2025
A new, function-driven definition of “clinical obesity” dramatically lowers global obesity prevalence rates compared to BMI-based estimates, raising implications for disease surveillance, prevention, and healthcare policy.
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US News & World Report 2025-2026 Rankings: The Top US Psychiatric Hospitals and Their Clinical Impact
Posted inMedical News Wellness & Lifestyle

US News & World Report 2025-2026 Rankings: The Top US Psychiatric Hospitals and Their Clinical Impact

Posted by By MedXY 07/30/2025
Massachusetts General Hospital leads the 2025-2026 US News psychiatric hospital rankings. Rankings highlight excellence in psychiatric care, but methodological nuances and clinical implications warrant closer examination.
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Managing Chronic Kidney Disease-Associated Pruritus: Advances and Clinical Strategies
Posted inClinical Updates Medical News

Managing Chronic Kidney Disease-Associated Pruritus: Advances and Clinical Strategies

Posted by By MedXY 07/30/2025
CKD-associated pruritus affects up to 85% of dialysis patients and significantly impairs quality of life. Stepwise management, including novel therapies like nemolizumab, is essential for effective symptom control and improved patient outcomes.
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  • Enhancing Metformin Efficacy and Tolerability in Prediabetes Through a Fermentable Carbohydrate-Rich Diet
  • Unlocking Precision Nutrition: Genetic Insights from the MIND Diet Trial for Cognitive Health
  • Long-Term Outcomes of the DASH Intervention in Nonobstructive Coronary Artery Disease: Follow-Up of the DISCO-CT Study
  • Dose-Dependent Enhancement of L-Tryptophan-Induced Gut Hormone Secretion and Appetite Suppression by Intraduodenal Calcium in Obesity
  • Decoding Metabolic Adaptation: Caloric Restriction’s Impact on Organ Size in the CALERIE 2 Trial
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