MedXY – Page 24

CDC Retracts Universal COVID-19 Vaccination Recommendation for Pregnancy: Clinical Context, Evidence, and Implications

By MedXY 07/30/2025

The CDC no longer universally recommends COVID-19 vaccination during pregnancy, prompting debate among clinicians as the FDA shifts vaccine composition to target the JN.1 variant. This article analyzes the evidence, rationale, and clinical implications.

Medical News Wellness & Lifestyle

Is There a Norovirus Vaccine on the Horizon? Scientific Progress, Challenges, and Future Directions

By MedXY 07/30/2025

Norovirus vaccines show promise in clinical trials, but scientific and logistical challenges remain. No approved vaccine exists yet, though novel approaches, including oral pills, are advancing development.

Clinical Updates Wellness & Lifestyle

Expanding Access to Chronic Pain Care: Telehealth and Online CBT-Based Interventions Show Promise

By MedXY 07/30/2025

Remote CBT-based interventions, delivered by telehealth or online modules, offer modest but significant improvements in pain and function for individuals with high-impact chronic pain, enhancing access to evidence-based care.

Clinical Updates Wellness & Lifestyle

Structured vs Self-Guided Multidomain Lifestyle Interventions for Cognitive Health: Insights from the US POINTER Randomized Clinical Trial

By MedXY 07/30/2025

A large US trial found that structured, intensive lifestyle interventions led to greater improvements in global cognition over two years compared to self-guided approaches among older adults at risk for cognitive decline.

Clinical Updates Wellness & Lifestyle

Demographic Data Gaps in FDA Authorization of AI-Based Devices for Alzheimer’s Disease and Related Dementias

By MedXY 07/30/2025

Limited demographic data transparency in FDA-authorized AI devices for Alzheimer’s may hinder equitable care and generalizability, highlighting a crucial need for improved dataset representativeness and regulatory oversight.

Clinical Updates Medical News

Influenza-Associated Acute Necrotizing Encephalopathy in US Children

By MedXY 07/30/2025

A multicenter US study highlights the devastating burden of influenza-associated acute necrotizing encephalopathy in children, with high mortality and disability rates despite aggressive therapy, underscoring the urgent need for prevention and standardized management.

Medical News Wellness & Lifestyle

Systemic Bias in AI: A Double-Edged Sword for Hospital Diagnostic Accuracy

By MedXY 07/30/2025

Systemically biased AI models can reduce clinicians' diagnostic accuracy, and explanations alone may not mitigate this harm, according to a multicenter study involving over 450 clinicians.

Clinical Updates Wellness & Lifestyle

Low Lupus Activity as a Predictive Target in Lupus Nephritis: A Clinical Appraisal of LLDAS

By MedXY 07/30/2025

Achieving low lupus disease activity (LLDAS) at 12 months is an attainable target in lupus nephritis and independently predicts reduced relapse risk and preserved renal function, supporting its potential as a future treatment goal.

Clinical Updates Wellness & Lifestyle

FDA Fast-Tracks Rezpegaldesleukin for Severe Alopecia Areata: Promise for a Challenging Disease

By MedXY 07/30/2025

The FDA has granted Fast Track status to rezpegaldesleukin (REZPEG), a novel biologic targeting regulatory T cells, for severe-to-very severe alopecia areata in patients aged ≥12 years. Phase 2b trial results are anticipated in December 2025.

Wellness & Lifestyle

How to Make Urology Care More Comfortable for Women

By MedXY 07/30/2025

Exploring why women often feel discomfort during urology visits and actionable strategies to create a more welcoming, effective clinical experience.