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Phase Ib Trial of Metformin Combined with Nivolumab in Refractory Solid Tumors: Safety, Dosage, and Preliminary Efficacy
Posted inClinical Updates Wellness & Lifestyle

Phase Ib Trial of Metformin Combined with Nivolumab in Refractory Solid Tumors: Safety, Dosage, and Preliminary Efficacy

Posted by By MedXY 09/15/2025
A phase Ib study evaluated the safety, optimal dosing, pharmacokinetics, and preliminary efficacy of metformin with nivolumab in refractory solid tumors, showing good tolerability and promising responses in a subset of patients.
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Oral Metformin in Non-Muscle-Invasive Bladder Cancer: Insights from a Phase II Marker Lesion Study
Posted inClinical Updates Wellness & Lifestyle

Oral Metformin in Non-Muscle-Invasive Bladder Cancer: Insights from a Phase II Marker Lesion Study

Posted by By MedXY 09/15/2025
A phase II trial assessing oral metformin for low-grade non-muscle-invasive bladder cancer (NMIBC) found minimal antitumor activity and no significant mechanistic changes, challenging metformin’s role as an intravesical therapeutic agent in this context.
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Optimizing Anesthesia in Elderly NSCLC Patients: Impact of Midazolam and Dexmedetomidine Co-Administration on Hemodynamics and Stress Response
Posted inClinical Updates Wellness & Lifestyle

Optimizing Anesthesia in Elderly NSCLC Patients: Impact of Midazolam and Dexmedetomidine Co-Administration on Hemodynamics and Stress Response

Posted by By MedXY 09/15/2025
Co-administering midazolam with dexmedetomidine in elderly NSCLC patients undergoing lobectomy enhances hemodynamic stability and reduces perioperative stress response, potentially improving recovery outcomes without increasing adverse events.
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Why Do Chimpanzees Rarely Get Cancer? Unveiling a Key Evolutionary Difference That Could Revolutionize Immunotherapy
Posted inMedical News Wellness & Lifestyle

Why Do Chimpanzees Rarely Get Cancer? Unveiling a Key Evolutionary Difference That Could Revolutionize Immunotherapy

Posted by By MedXY 09/14/2025
New research reveals that a protein called plasmin weakens human immune response against cancer compared to chimpanzees, offering promising strategies to enhance cancer immunotherapy.
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How Micronutrients Have Shaped Human DNA: Insights from Global Genetic Adaptations
Posted inMedical News Wellness & Lifestyle

How Micronutrients Have Shaped Human DNA: Insights from Global Genetic Adaptations

Posted by By MedXY 09/14/2025
A recent study reveals how essential micronutrients like iron, calcium, and zinc influenced human evolution by driving genetic adaptations to environmental nutrient availability across populations worldwide.
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Sudden Death Is Not So Sudden: Understanding, Preventing, and Responding to Cardiac Arrest
Posted inMedical News Wellness & Lifestyle

Sudden Death Is Not So Sudden: Understanding, Preventing, and Responding to Cardiac Arrest

Posted by By MedXY 09/14/2025
Sudden death, often caused by heart conditions, is typically the culmination of gradual damage. This article explores warning signs, emergency response, and crucial prevention strategies to protect your heart and save lives.
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The Ginger Miracle? Exploring the Anti-Aging Potential of Ginger and What the Science Really Says
Posted inMedical News Wellness & Lifestyle

The Ginger Miracle? Exploring the Anti-Aging Potential of Ginger and What the Science Really Says

Posted by By MedXY 09/14/2025
Recent studies suggest a compound in ginger may clear half of aging cells in two days, but practical benefits and safety concerns warrant cautious optimism. Here's a science-based look at ginger and aging.
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Citrate: The New Molecular Key to Reversing Vascular Aging and Combating Cardiovascular Disease
Posted inMedical News Wellness & Lifestyle

Citrate: The New Molecular Key to Reversing Vascular Aging and Combating Cardiovascular Disease

Posted by By MedXY 09/14/2025
Recent research reveals that citrate, a natural compound found in citrus fruits, may significantly reverse vascular aging and reduce the risk of cardiovascular diseases by restoring mitochondrial function and vascular elasticity.
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Enhanced Gait Rehabilitation in Chronic Stroke: Combining High-Intensity Interval Training with Robot-Assisted Gait Therapy
Posted inClinical Updates Wellness & Lifestyle

Enhanced Gait Rehabilitation in Chronic Stroke: Combining High-Intensity Interval Training with Robot-Assisted Gait Therapy

Posted by By MedXY 09/14/2025
A randomized controlled trial demonstrates that combining high-intensity interval training with robot-assisted gait therapy significantly improves gait speed, balance, and lower limb function in patients with chronic stroke compared to treadmill therapy alone.
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Enhanced Adenoma Detection in Water Exchange Colonoscopy Using AI: Insights from a Two-Center Randomized Trial
Posted inClinical Updates Wellness & Lifestyle

Enhanced Adenoma Detection in Water Exchange Colonoscopy Using AI: Insights from a Two-Center Randomized Trial

Posted by By MedXY 09/14/2025
A multicenter trial demonstrated that integrating AI-based computer-aided detection with water exchange colonoscopy significantly increases adenomas per colonoscopy without prolonging procedure time or increasing non-neoplastic lesion detection.
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  • Early-Life Blueberry Consumption: Potential Benefits for Infant Allergy Resolution, Immune Modulation, and Gut Microbiome Development
  • Unlocking Better Sleep: How Daily Walnut Consumption Enhances Melatonin Metabolism and Sleep Quality in Young Adults
  • Enhanced Therapeutic Benefits of Combined Metformin and Curcumin in Women with Polycystic Ovary Syndrome: Results from a Factorial Clinical Trial
  • Metformin with or without Mediterranean Diet Significantly Reduces Diabetes Risk in Metabolic Syndrome: Insights from the MeMeMe Trial
  • Innovative Combination Therapy in Recurrent Advanced Endometrial Cancer: Insights from the ENDOLA Phase I/II Trial
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