Clinical Updates – Page 15

Opioid Prescribing Down, Imaging Steady: Patterns in US ED Management of Low Back Pain, 2016–2022

By MedXY 07/30/2025

A large national study shows opioid prescribing for ED low back pain fell sharply from 2016 to 2022, while radiograph use remained high and unchanged.

Clinical Updates Wellness & Lifestyle

Rising Threat: Triazole-Resistant Aspergillus fumigatus and the Challenge of Fungal Antimicrobial Resistance

By MedXY 07/30/2025

A 29-year genomic study reveals increasing genetic diversity and prevalence of triazole-resistant Aspergillus fumigatus, raising concerns for clinical management and highlighting the need for novel diagnostics and antifungal strategies.

Clinical Updates Wellness & Lifestyle

Novel HIV Peptides Identified During Treatment Interruption May Inform Next-Generation Therapeutic Strategies

By MedXY 07/30/2025

Discovery of genetically conserved, mutation-intolerant HIV peptides in rebound virus during analytic treatment interruption highlights new avenues for mRNA vaccine development and functional HIV cure strategies.

Clinical Updates Medical News

Managing Chronic Kidney Disease-Associated Pruritus: Advances and Clinical Strategies

By MedXY 07/30/2025

CKD-associated pruritus affects up to 85% of dialysis patients and significantly impairs quality of life. Stepwise management, including novel therapies like nemolizumab, is essential for effective symptom control and improved patient outcomes.

Clinical Updates Wellness & Lifestyle

Elevated Colorectal Cancer Risk in Patients with IBD and Primary Sclerosing Cholangitis: Insights from a National Swedish Cohort

By MedXY 07/30/2025

Patients with inflammatory bowel disease (IBD), particularly those with primary sclerosing cholangitis (PSC) or early-onset disease, face a substantially increased risk of colorectal cancer (CRC), emphasizing the need for vigilant surveillance.

Clinical Updates Wellness & Lifestyle

Antibody-Drug Conjugates in Breast Cancer: Efficacy, Toxicity, and Evolving Management Strategies

By MedXY 07/30/2025

Antibody-drug conjugates (ADCs) have transformed breast cancer therapy but bring notable toxicity risks. This review examines the clinical evidence, adverse event management, and future directions for optimizing ADC use.

Clinical Updates Wellness & Lifestyle

FDA Expands Skytrofa Approval to Adults with Growth Hormone Deficiency: Clinical and Practice Implications

By MedXY 07/30/2025

Once-weekly lonapegsomatropin (Skytrofa) is now FDA-approved for adult growth hormone deficiency, offering a more convenient alternative to daily injections with demonstrated efficacy and safety.

Clinical Updates Medical News

Physical Activity Trajectories Before and After Cardiovascular Disease: Insights from the CARDIA Study

By MedXY 07/29/2025

Longitudinal data from CARDIA reveal declining physical activity before and after CVD events, with pronounced disparities among Black women, highlighting the need for targeted interventions across the life course.

Clinical Updates Medical News

Structured Lifestyle Intervention Shows Superior Cognitive Benefits in At-Risk Older Adults: Insights from the US POINTER Trial

By MedXY 07/29/2025

A large US trial shows that intensive, structured lifestyle programs yield greater cognitive improvement in at-risk older adults compared to self-guided approaches, though both are beneficial.

Clinical Updates Wellness & Lifestyle

Subclinical Primary Aldosteronism: A Hidden Driver of Cardiovascular Risk Beyond Blood Pressure

By MedXY 07/29/2025

Emerging evidence links subclinical primary aldosteronism to significantly increased cardiovascular risk, even in normotensive individuals, highlighting the need for refined screening and personalized hypertension management.